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NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation.
Huth M, Santini L, Galimberti E, Ramesmayer J, Titz-Teixeira F, Sehlke R, Oberhuemer M, Stummer S, Herzog V, Garmhausen M, Romeike M, Chugunova A, Leesch F, Holcik L, Weipoltshammer K, Lackner A, Schoefer C, von Haeseler A, Buecker C, Pauli A, Ameres SL, Smith A, Beyer A, Leeb M. Huth M, et al. Among authors: sehlke r. Genes Dev. 2022 Mar 1;36(5-6):348-367. doi: 10.1101/gad.347690.120. Epub 2022 Mar 3. Genes Dev. 2022. PMID: 35241478 Free PMC article.
Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency.
Lackner A, Sehlke R, Garmhausen M, Giuseppe Stirparo G, Huth M, Titz-Teixeira F, van der Lelij P, Ramesmayer J, Thomas HF, Ralser M, Santini L, Galimberti E, Sarov M, Stewart AF, Smith A, Beyer A, Leeb M. Lackner A, et al. Among authors: sehlke r. EMBO J. 2021 Apr 15;40(8):e105776. doi: 10.15252/embj.2020105776. Epub 2021 Mar 9. EMBO J. 2021. PMID: 33687089 Free PMC article.