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Rab5 is necessary for the biogenesis of the endolysosomal system in vivo.
Zeigerer A, Gilleron J, Bogorad RL, Marsico G, Nonaka H, Seifert S, Epstein-Barash H, Kuchimanchi S, Peng CG, Ruda VM, Del Conte-Zerial P, Hengstler JG, Kalaidzidis Y, Koteliansky V, Zerial M. Zeigerer A, et al. Among authors: seifert s. Nature. 2012 May 23;485(7399):465-70. doi: 10.1038/nature11133. Nature. 2012. PMID: 22622570
Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape.
Gilleron J, Querbes W, Zeigerer A, Borodovsky A, Marsico G, Schubert U, Manygoats K, Seifert S, Andree C, Stöter M, Epstein-Barash H, Zhang L, Koteliansky V, Fitzgerald K, Fava E, Bickle M, Kalaidzidis Y, Akinc A, Maier M, Zerial M. Gilleron J, et al. Among authors: seifert s. Nat Biotechnol. 2013 Jul;31(7):638-46. doi: 10.1038/nbt.2612. Epub 2013 Jun 23. Nat Biotechnol. 2013. PMID: 23792630
Regulation of liver metabolism by the endosomal GTPase Rab5.
Zeigerer A, Bogorad RL, Sharma K, Gilleron J, Seifert S, Sales S, Berndt N, Bulik S, Marsico G, D'Souza RCJ, Lakshmanaperumal N, Meganathan K, Natarajan K, Sachinidis A, Dahl A, Holzhütter HG, Shevchenko A, Mann M, Koteliansky V, Zerial M. Zeigerer A, et al. Among authors: seifert s. Cell Rep. 2015 May 12;11(6):884-892. doi: 10.1016/j.celrep.2015.04.018. Epub 2015 Apr 30. Cell Rep. 2015. PMID: 25937276 Free article.
Identification of siRNA delivery enhancers by a chemical library screen.
Gilleron J, Paramasivam P, Zeigerer A, Querbes W, Marsico G, Andree C, Seifert S, Amaya P, Stöter M, Koteliansky V, Waldmann H, Fitzgerald K, Kalaidzidis Y, Akinc A, Maier MA, Manoharan M, Bickle M, Zerial M. Gilleron J, et al. Among authors: seifert s. Nucleic Acids Res. 2015 Sep 18;43(16):7984-8001. doi: 10.1093/nar/gkv762. Epub 2015 Jul 28. Nucleic Acids Res. 2015. PMID: 26220182 Free PMC article.
Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression.
Segovia-Miranda F, Morales-Navarrete H, Kücken M, Moser V, Seifert S, Repnik U, Rost F, Brosch M, Hendricks A, Hinz S, Röcken C, Lütjohann D, Kalaidzidis Y, Schafmayer C, Brusch L, Hampe J, Zerial M. Segovia-Miranda F, et al. Among authors: seifert s. Nat Med. 2019 Dec;25(12):1885-1893. doi: 10.1038/s41591-019-0660-7. Epub 2019 Dec 2. Nat Med. 2019. PMID: 31792455 Free PMC article.
Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads.
Belicova L, Repnik U, Delpierre J, Gralinska E, Seifert S, Valenzuela JI, Morales-Navarrete HA, Franke C, Räägel H, Shcherbinina E, Prikazchikova T, Koteliansky V, Vingron M, Kalaidzidis YL, Zatsepin T, Zerial M. Belicova L, et al. Among authors: seifert s. J Cell Biol. 2021 Oct 4;220(10):e202103003. doi: 10.1083/jcb.202103003. Epub 2021 Jul 30. J Cell Biol. 2021. PMID: 34328499 Free PMC article.
471 results