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Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis.
Badenes M, Amin A, González-García I, Félix I, Burbridge E, Cavadas M, Ortega FJ, de Carvalho É, Faísca P, Carobbio S, Seixas E, Pedroso D, Neves-Costa A, Moita LF, Fernández-Real JM, Vidal-Puig A, Domingos A, López M, Adrain C. Badenes M, et al. Among authors: seixas e. Mol Metab. 2020 Jan;31:67-84. doi: 10.1016/j.molmet.2019.10.006. Epub 2019 Oct 31. Mol Metab. 2020. PMID: 31918923 Free PMC article.
Brain-Sparing Sympathofacilitators Mitigate Obesity without Adverse Cardiovascular Effects.
Mahú I, Barateiro A, Rial-Pensado E, Martinéz-Sánchez N, Vaz SH, Cal PMSD, Jenkins B, Rodrigues T, Cordeiro C, Costa MF, Mendes R, Seixas E, Pereira MMA, Kubasova N, Gres V, Morris I, Temporão C, Olivares M, Sanz Y, Koulman A, Corzana F, Sebastião AM, López M, Bernardes GJL, Domingos AI. Mahú I, et al. Among authors: seixas e. Cell Metab. 2020 Jun 2;31(6):1120-1135.e7. doi: 10.1016/j.cmet.2020.04.013. Epub 2020 May 12. Cell Metab. 2020. PMID: 32402266 Free PMC article.
CXCL5-mediated recruitment of neutrophils into the peritoneal cavity of Gdf15-deficient mice protects against abdominal sepsis.
Santos I, Colaço HG, Neves-Costa A, Seixas E, Velho TR, Pedroso D, Barros A, Martins R, Carvalho N, Payen D, Weis S, Yi HS, Shong M, Moita LF. Santos I, et al. Among authors: seixas e. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12281-12287. doi: 10.1073/pnas.1918508117. Epub 2020 May 18. Proc Natl Acad Sci U S A. 2020. PMID: 32424099 Free PMC article.
Tetracycline Antibiotics Induce Host-Dependent Disease Tolerance to Infection.
Colaço HG, Barros A, Neves-Costa A, Seixas E, Pedroso D, Velho T, Willmann KL, Faisca P, Grabmann G, Yi HS, Shong M, Benes V, Weis S, Köcher T, Moita LF. Colaço HG, et al. Among authors: seixas e. Immunity. 2021 Jan 12;54(1):53-67.e7. doi: 10.1016/j.immuni.2020.09.011. Epub 2020 Oct 14. Immunity. 2021. PMID: 33058782 Free PMC article.
Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine.
Pirzgalska RM, Seixas E, Seidman JS, Link VM, Sánchez NM, Mahú I, Mendes R, Gres V, Kubasova N, Morris I, Arús BA, Larabee CM, Vasques M, Tortosa F, Sousa AL, Anandan S, Tranfield E, Hahn MK, Iannacone M, Spann NJ, Glass CK, Domingos AI. Pirzgalska RM, et al. Among authors: seixas e. Nat Med. 2017 Nov;23(11):1309-1318. doi: 10.1038/nm.4422. Epub 2017 Oct 9. Nat Med. 2017. PMID: 29035364 Free PMC article.
Sympathetic neuro-adipose connections mediate leptin-driven lipolysis.
Zeng W, Pirzgalska RM, Pereira MM, Kubasova N, Barateiro A, Seixas E, Lu YH, Kozlova A, Voss H, Martins GG, Friedman JM, Domingos AI. Zeng W, et al. Among authors: seixas e. Cell. 2015 Sep 24;163(1):84-94. doi: 10.1016/j.cell.2015.08.055. Cell. 2015. PMID: 26406372 Free article.
A hypometabolic defense strategy against malaria.
Ramos S, Ademolue TW, Jentho E, Wu Q, Guerra J, Martins R, Pires G, Weis S, Carlos AR, Mahú I, Seixas E, Duarte D, Rajas F, Cardoso S, Sousa AGG, Lilue J, Paixão T, Mithieux G, Nogueira F, Soares MP. Ramos S, et al. Among authors: seixas e. Cell Metab. 2022 Aug 2;34(8):1183-1200.e12. doi: 10.1016/j.cmet.2022.06.011. Epub 2022 Jul 15. Cell Metab. 2022. PMID: 35841892 Free article.
Heme oxygenase-1 affords protection against noncerebral forms of severe malaria.
Seixas E, Gozzelino R, Chora A, Ferreira A, Silva G, Larsen R, Rebelo S, Penido C, Smith NR, Coutinho A, Soares MP. Seixas E, et al. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15837-42. doi: 10.1073/pnas.0903419106. Epub 2009 Aug 17. Proc Natl Acad Sci U S A. 2009. PMID: 19706490 Free PMC article.
49 results