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Lapatinib plus Capecitabine versus Trastuzumab plus Capecitabine in the Treatment of Human Epidermal Growth Factor Receptor 2-positive Metastatic Breast Cancer with Central Nervous System Metastases for Patients Currently or Previously Treated with Trastuzumab (LANTERN): a Phase II Randomised Trial.
Seligmann JF, Wright-Hughes A, Pottinger A, Velikova G, Oughton JB, Murden G, Rizwanullah M, Price C, Passant H, Heudtlass P, Marshall H, Johnston S, Dodwell D. Seligmann JF, et al. Clin Oncol (R Coll Radiol). 2020 Oct;32(10):656-664. doi: 10.1016/j.clon.2020.06.003. Epub 2020 Jun 27. Clin Oncol (R Coll Radiol). 2020. PMID: 32600919 Clinical Trial.
Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial.
Seymour MT, Brown SR, Middleton G, Maughan T, Richman S, Gwyther S, Lowe C, Seligmann JF, Wadsley J, Maisey N, Chau I, Hill M, Dawson L, Falk S, O'Callaghan A, Benstead K, Chambers P, Oliver A, Marshall H, Napp V, Quirke P. Seymour MT, et al. Among authors: seligmann jf. Lancet Oncol. 2013 Jul;14(8):749-59. doi: 10.1016/S1470-2045(13)70163-3. Epub 2013 May 29. Lancet Oncol. 2013. PMID: 23725851 Free PMC article. Clinical Trial.
Big Data and Colorectal Cancer: the Revolution will be Personalised.
Williams CJM, Seligmann JF. Williams CJM, et al. Among authors: seligmann jf. Clin Oncol (R Coll Radiol). 2024 Apr;36(4):206-210. doi: 10.1016/j.clon.2024.01.010. Epub 2024 Jan 23. Clin Oncol (R Coll Radiol). 2024. PMID: 38281865 No abstract available.
Associations between AI-Assisted Tumor Amphiregulin and Epiregulin IHC and Outcomes from Anti-EGFR Therapy in the Routine Management of Metastatic Colorectal Cancer.
Williams CJM, Elliott F, Sapanara N, Aghaei F, Zhang L, Muranyi A, Yan D, Bai I, Zhao Z, Shires M, Wood HM, Richman SD, Hemmings G, Hale M, Bottomley D, Galvin L, Cartlidge C, Dance S, Bacon CM, Mansfield L, Young-Zvandasara K, Sudan A, Lambert K, Bibby I, Coupland SE, Montazeri A, Kipling N, Hughes K, Cross SS, Dewdney A, Pheasey L, Leng C, Gochera T, Mangham DC, Saunders M, Pritchard M, Stott H, Mukherjee A, Ilyas M, Silverman R, Hyland G, Sculthorpe D, Thornton K, Gould I, O'Callaghan A, Brown N, Turnbull S, Shaw L, Seymour MT, West NP, Seligmann JF, Singh S, Shanmugam K, Quirke P. Williams CJM, et al. Among authors: seligmann jf. Clin Cancer Res. 2023 Oct 13;29(20):4153-4165. doi: 10.1158/1078-0432.CCR-23-0859. Clin Cancer Res. 2023. PMID: 37363997 Free PMC article.
FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty.
Platt JR, Todd OM, Hall P, Craig Z, Quyn A, Seymour M, Braun M, Roodhart J, Punt C, Christou N, Taieb J, Karoui M, Brown J, Cairns DA, Morton D, Gilbert A, Seligmann JF. Platt JR, et al. Among authors: seligmann jf. ESMO Open. 2023 Feb;8(1):100642. doi: 10.1016/j.esmoop.2022.100642. Epub 2022 Dec 20. ESMO Open. 2023. PMID: 36549127 Free PMC article. Review.
Inhibition of WEE1 Is Effective in TP53- and RAS-Mutant Metastatic Colorectal Cancer: A Randomized Trial (FOCUS4-C) Comparing Adavosertib (AZD1775) With Active Monitoring.
Seligmann JF, Fisher DJ, Brown LC, Adams RA, Graham J, Quirke P, Richman SD, Butler R, Domingo E, Blake A, Yates E, Braun M, Collinson F, Jones R, Brown E, de Winton E, Humphrey TC, Parmar M, Kaplan R, Wilson RH, Seymour M, Maughan TS; FOCUS4 Trial Investigators. Seligmann JF, et al. J Clin Oncol. 2021 Nov 20;39(33):3705-3715. doi: 10.1200/JCO.21.01435. Epub 2021 Sep 18. J Clin Oncol. 2021. PMID: 34538072 Free PMC article. Clinical Trial.
Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial.
Adams RA, Fisher DJ, Graham J, Seligmann JF, Seymour M, Kaplan R, Yates E, Parmar M, Richman SD, Quirke P, Butler R, Brown E, Collinson F, Falk S, Wasan H, Shiu KK, Middleton G, Samuel L, Wilson RH, Brown LC, Maughan TS; FOCUS4 Trial Investigators. Adams RA, et al. Among authors: seligmann jf. J Clin Oncol. 2021 Nov 20;39(33):3693-3704. doi: 10.1200/JCO.21.01436. Epub 2021 Sep 13. J Clin Oncol. 2021. PMID: 34516759 Free PMC article. Clinical Trial.
18 results