Selkoe DJ - Search Results

1

Polyunsaturated fatty acids induce alpha-synuclein-related pathogenic changes in neuronal cells.

Assayag K, Yakunin E, Loeb V, Selkoe DJ, Sharon R. Assayag K, et al. Among authors: selkoe dj. Am J Pathol. 2007 Dec;171(6):2000-11. doi: 10.2353/ajpath.2007.070373. Epub 2007 Nov 30. Am J Pathol. 2007. PMID: 18055555 Free PMC article.

2

alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins.

Sharon R, Goldberg MS, Bar-Josef I, Betensky RA, Shen J, Selkoe DJ. Sharon R, et al. Among authors: selkoe dj. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9110-5. doi: 10.1073/pnas.171300598. Proc Natl Acad Sci U S A. 2001. PMID: 11481478 Free PMC article.

3

Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies.

Schlossmacher MG, Frosch MP, Gai WP, Medina M, Sharma N, Forno L, Ochiishi T, Shimura H, Sharon R, Hattori N, Langston JW, Mizuno Y, Hyman BT, Selkoe DJ, Kosik KS. Schlossmacher MG, et al. Among authors: selkoe dj. Am J Pathol. 2002 May;160(5):1655-67. doi: 10.1016/S0002-9440(10)61113-3. Am J Pathol. 2002. PMID: 12000718 Free PMC article.

4

The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease.

Sharon R, Bar-Joseph I, Frosch MP, Walsh DM, Hamilton JA, Selkoe DJ. Sharon R, et al. Among authors: selkoe dj. Neuron. 2003 Feb 20;37(4):583-95. doi: 10.1016/s0896-6273(03)00024-2. Neuron. 2003. PMID: 12597857 Free article.

5

Altered fatty acid composition of dopaminergic neurons expressing alpha-synuclein and human brains with alpha-synucleinopathies.

Sharon R, Bar-Joseph I, Mirick GE, Serhan CN, Selkoe DJ. Sharon R, et al. Among authors: selkoe dj. J Biol Chem. 2003 Dec 12;278(50):49874-81. doi: 10.1074/jbc.M309127200. Epub 2003 Sep 23. J Biol Chem. 2003. PMID: 14507911 Free article.

6

Alpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recycling.

Ben Gedalya T, Loeb V, Israeli E, Altschuler Y, Selkoe DJ, Sharon R. Ben Gedalya T, et al. Among authors: selkoe dj. Traffic. 2009 Feb;10(2):218-34. doi: 10.1111/j.1600-0854.2008.00853.x. Epub 2008 Oct 31. Traffic. 2009. PMID: 18980610 Free PMC article.

7

Α-synuclein neuropathology is controlled by nuclear hormone receptors and enhanced by docosahexaenoic acid in a mouse model for Parkinson's disease.

Yakunin E, Loeb V, Kisos H, Biala Y, Yehuda S, Yaari Y, Selkoe DJ, Sharon R. Yakunin E, et al. Among authors: selkoe dj. Brain Pathol. 2012 May;22(3):280-94. doi: 10.1111/j.1750-3639.2011.00530.x. Epub 2011 Oct 31. Brain Pathol. 2012. PMID: 21929559 Free PMC article.

8

Microinjection of synthetic amyloid beta-protein in monkey cerebral cortex fails to produce acute neurotoxicity.

Podlisny MB, Stephenson DT, Frosch MP, Tolan DR, Lieberburg I, Clemens JA, Selkoe DJ. Podlisny MB, et al. Among authors: selkoe dj. Am J Pathol. 1993 Jan;142(1):17-24. Am J Pathol. 1993. PMID: 8424453 Free PMC article.

9

Defining the native state of α-synuclein.

Selkoe D, Dettmer U, Luth E, Kim N, Newman A, Bartels T. Selkoe D, et al. Neurodegener Dis. 2014;13(2-3):114-7. doi: 10.1159/000355516. Epub 2013 Oct 30. Neurodegener Dis. 2014. PMID: 24192542 Review.

10

New insights into cellular α-synuclein homeostasis in health and disease.

Dettmer U, Selkoe D, Bartels T. Dettmer U, et al. Curr Opin Neurobiol. 2016 Feb;36:15-22. doi: 10.1016/j.conb.2015.07.007. Epub 2015 Aug 15. Curr Opin Neurobiol. 2016. PMID: 26282834 Review.

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