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Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells.
Morris V, Wang D, Li Z, Marion W, Hughes T, Sousa P, Harada T, Sui SH, Naumenko S, Kalfon J, Sensharma P, Falchetti M, Vinicius da Silva R, Candelli T, Schneider P, Margaritis T, Holstege FCP, Pikman Y, Harris M, Stam RW, Orkin SH, Koehler AN, Shalek AK, North TE, Pimkin M, Daley GQ, Lummertz da Rocha E, Rowe RG. Morris V, et al. Among authors: sensharma p. Cell Rep. 2022 Apr 26;39(4):110752. doi: 10.1016/j.celrep.2022.110752. Cell Rep. 2022. PMID: 35476984 Free PMC article.
RUNX1 mutations mitigate quiescence to promote transformation of hematopoietic progenitors in Fanconi anemia.
Marion W, Koppe T, Chen CC, Wang D, Frenis K, Fierstein S, Sensharma P, Aumais O, Peters M, Ruiz-Torres S, Chihanga T, Boettcher S, Shimamura A, Bauer DE, Schlaeger T, Wells SI, Ebert BL, Starczynowski D, da Rocha EL, Rowe RG. Marion W, et al. Among authors: sensharma p. Leukemia. 2023 Aug;37(8):1698-1708. doi: 10.1038/s41375-023-01945-6. Epub 2023 Jun 30. Leukemia. 2023. PMID: 37391485
Low mortality oxidative stress murine chronic wound model.
Panayi AC, Endo Y, Karvar M, Sensharma P, Haug V, Fu S, Mi B, An Y, Orgill DP. Panayi AC, et al. Among authors: sensharma p. BMJ Open Diabetes Res Care. 2020 Sep;8(1):e001221. doi: 10.1136/bmjdrc-2020-001221. BMJ Open Diabetes Res Care. 2020. PMID: 32900696 Free PMC article.
Hydrogel-Embedded Quantum Dot-Transcription Factor Sensors for Quantitative Progesterone Detection.
Chen M, Grazon C, Sensharma P, Nguyen TT, Feng Y, Chern M, Baer RC, Varongchayakul N, Cook K, Lecommandoux S, Klapperich CM, Galagan JE, Dennis AM, Grinstaff MW. Chen M, et al. Among authors: sensharma p. ACS Appl Mater Interfaces. 2020 Sep 30;12(39):43513-43521. doi: 10.1021/acsami.0c13489. Epub 2020 Sep 18. ACS Appl Mater Interfaces. 2020. PMID: 32893612 Free article.