Seshagiri S - Search Results

1

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO.

Zhou H, Wertz I, O'Rourke K, Ultsch M, Seshagiri S, Eby M, Xiao W, Dixit VM. Zhou H, et al. Among authors: seshagiri s. Nature. 2004 Jan 8;427(6970):167-71. doi: 10.1038/nature02273. Epub 2003 Dec 24. Nature. 2004. PMID: 14695475

2

Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP.

Seshagiri S, Vucic D, Lee J, Dixit VM. Seshagiri S, et al. J Biol Chem. 1999 Dec 17;274(51):36769-73. doi: 10.1074/jbc.274.51.36769. J Biol Chem. 1999. PMID: 10593985 Free article.

3

Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma.

Uren AG, O'Rourke K, Aravind LA, Pisabarro MT, Seshagiri S, Koonin EV, Dixit VM. Uren AG, et al. Among authors: seshagiri s. Mol Cell. 2000 Oct;6(4):961-7. doi: 10.1016/s1097-2765(00)00094-0. Mol Cell. 2000. PMID: 11090634 Free article.

4

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling.

Wertz IE, O'Rourke KM, Zhou H, Eby M, Aravind L, Seshagiri S, Wu P, Wiesmann C, Baker R, Boone DL, Ma A, Koonin EV, Dixit VM. Wertz IE, et al. Among authors: seshagiri s. Nature. 2004 Aug 5;430(7000):694-9. doi: 10.1038/nature02794. Epub 2004 Jul 18. Nature. 2004. PMID: 15258597

5

Oncogenic BRAF is required for tumor growth and maintenance in melanoma models.

Hoeflich KP, Gray DC, Eby MT, Tien JY, Wong L, Bower J, Gogineni A, Zha J, Cole MJ, Stern HM, Murray LJ, Davis DP, Seshagiri S. Hoeflich KP, et al. Among authors: seshagiri s. Cancer Res. 2006 Jan 15;66(2):999-1006. doi: 10.1158/0008-5472.CAN-05-2720. Cancer Res. 2006. PMID: 16424035

6

ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage.

Dornan D, Shimizu H, Mah A, Dudhela T, Eby M, O'rourke K, Seshagiri S, Dixit VM. Dornan D, et al. Among authors: seshagiri s. Science. 2006 Aug 25;313(5790):1122-6. doi: 10.1126/science.1127335. Science. 2006. PMID: 16931761

7

Regulation of ERK3/MAPK6 expression by BRAF.

Hoeflich KP, Eby MT, Forrest WF, Gray DC, Tien JY, Stern HM, Murray LJ, Davis DP, Modrusan Z, Seshagiri S. Hoeflich KP, et al. Among authors: seshagiri s. Int J Oncol. 2006 Oct;29(4):839-49. Int J Oncol. 2006. PMID: 16964379

8

Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection.

Peters BA, Kan Z, Sebisanovic D, Pujara K, Wang Z, Hong P, Chow B, Stinson J, Carlton VE, Pham TQ, Stern H, Waring P, Hillan KJ, Eberhard DA, de Sauvage F, Zheng J, Faham M, Seshagiri S. Peters BA, et al. Among authors: seshagiri s. Nat Methods. 2007 Sep;4(9):713-5. doi: 10.1038/nmeth1081. Epub 2007 Aug 19. Nat Methods. 2007. PMID: 17704782

9

Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation.

Jaiswal BS, Janakiraman V, Kljavin NM, Chaudhuri S, Stern HM, Wang W, Kan Z, Dbouk HA, Peters BA, Waring P, Dela Vega T, Kenski DM, Bowman KK, Lorenzo M, Li H, Wu J, Modrusan Z, Stinson J, Eby M, Yue P, Kaminker JS, de Sauvage FJ, Backer JM, Seshagiri S. Jaiswal BS, et al. Among authors: seshagiri s. Cancer Cell. 2009 Dec 8;16(6):463-74. doi: 10.1016/j.ccr.2009.10.016. Cancer Cell. 2009. PMID: 19962665 Free PMC article.

10

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.

Hatzivassiliou G, Song K, Yen I, Brandhuber BJ, Anderson DJ, Alvarado R, Ludlam MJ, Stokoe D, Gloor SL, Vigers G, Morales T, Aliagas I, Liu B, Sideris S, Hoeflich KP, Jaiswal BS, Seshagiri S, Koeppen H, Belvin M, Friedman LS, Malek S. Hatzivassiliou G, et al. Among authors: seshagiri s. Nature. 2010 Mar 18;464(7287):431-5. doi: 10.1038/nature08833. Epub 2010 Feb 3. Nature. 2010. PMID: 20130576

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