Settleman J - Search Results

1

Neurite outgrowth from PC12 cells by basic fibroblast growth factor (bFGF) is mediated by RhoA inactivation through p190RhoGAP and ARAP3.

Jeon CY, Kim HJ, Morii H, Mori N, Settleman J, Lee JY, Kim J, Kim SC, Park JB. Jeon CY, et al. Among authors: settleman j. J Cell Physiol. 2010 Sep;224(3):786-94. doi: 10.1002/jcp.22184. J Cell Physiol. 2010. PMID: 20578246

2

Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane.

Bradley WD, Hernández SE, Settleman J, Koleske AJ. Bradley WD, et al. Among authors: settleman j. Mol Biol Cell. 2006 Nov;17(11):4827-36. doi: 10.1091/mbc.e06-02-0132. Epub 2006 Sep 13. Mol Biol Cell. 2006. PMID: 16971514 Free PMC article.

3

Inhibition of Rho via Arg and p190RhoGAP in the postnatal mouse hippocampus regulates dendritic spine maturation, synapse and dendrite stability, and behavior.

Sfakianos MK, Eisman A, Gourley SL, Bradley WD, Scheetz AJ, Settleman J, Taylor JR, Greer CA, Williamson A, Koleske AJ. Sfakianos MK, et al. Among authors: settleman j. J Neurosci. 2007 Oct 10;27(41):10982-92. doi: 10.1523/JNEUROSCI.0793-07.2007. J Neurosci. 2007. PMID: 17928439 Free PMC article.

4

SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway.

Kontaridis MI, Eminaga S, Fornaro M, Zito CI, Sordella R, Settleman J, Bennett AM. Kontaridis MI, et al. Among authors: settleman j. Mol Cell Biol. 2004 Jun;24(12):5340-52. doi: 10.1128/MCB.24.12.5340-5352.2004. Mol Cell Biol. 2004. PMID: 15169898 Free PMC article.

5

p190RhoGAP is the convergence point of adhesion signals from alpha 5 beta 1 integrin and syndecan-4.

Bass MD, Morgan MR, Roach KA, Settleman J, Goryachev AB, Humphries MJ. Bass MD, et al. Among authors: settleman j. J Cell Biol. 2008 Jun 16;181(6):1013-26. doi: 10.1083/jcb.200711129. Epub 2008 Jun 9. J Cell Biol. 2008. PMID: 18541700 Free PMC article.

6

Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion.

Shen CH, Chen HY, Lin MS, Li FY, Chang CC, Kuo ML, Settleman J, Chen RH. Shen CH, et al. Among authors: settleman j. Cancer Res. 2008 Oct 1;68(19):7779-87. doi: 10.1158/0008-5472.CAN-08-0997. Cancer Res. 2008. PMID: 18829532

7

c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation.

Chang JH, Gill S, Settleman J, Parsons SJ. Chang JH, et al. Among authors: settleman j. J Cell Biol. 1995 Jul;130(2):355-68. doi: 10.1083/jcb.130.2.355. J Cell Biol. 1995. PMID: 7542246 Free PMC article.

8

Rnd proteins function as RhoA antagonists by activating p190 RhoGAP.

Wennerberg K, Forget MA, Ellerbroek SM, Arthur WT, Burridge K, Settleman J, Der CJ, Hansen SH. Wennerberg K, et al. Among authors: settleman j. Curr Biol. 2003 Jul 1;13(13):1106-15. doi: 10.1016/s0960-9822(03)00418-4. Curr Biol. 2003. PMID: 12842009 Free PMC article.

9

Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva.

Gupta P, Emdad L, Lebedeva IV, Sarkar D, Dent P, Curiel DT, Settleman J, Fisher PB. Gupta P, et al. Among authors: settleman j. J Cell Physiol. 2008 Jun;215(3):827-36. doi: 10.1002/jcp.21369. J Cell Physiol. 2008. PMID: 18270968

10

The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization.

Vincent S, Settleman J. Vincent S, et al. Among authors: settleman j. Mol Cell Biol. 1997 Apr;17(4):2247-56. doi: 10.1128/MCB.17.4.2247. Mol Cell Biol. 1997. PMID: 9121475 Free PMC article.

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