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Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14.
Ames RS, Sarau HM, Chambers JK, Willette RN, Aiyar NV, Romanic AM, Louden CS, Foley JJ, Sauermelch CF, Coatney RW, Ao Z, Disa J, Holmes SD, Stadel JM, Martin JD, Liu WS, Glover GI, Wilson S, McNulty DE, Ellis CE, Elshourbagy NA, Shabon U, Trill JJ, Hay DW, Ohlstein EH, Bergsma DJ, Douglas SA. Ames RS, et al. Among authors: shabon u. Nature. 1999 Sep 16;401(6750):282-6. doi: 10.1038/45809. Nature. 1999. PMID: 10499587
The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects.
Johns DG, Behm DJ, Walker DJ, Ao Z, Shapland EM, Daniels DA, Riddick M, Dowell S, Staton PC, Green P, Shabon U, Bao W, Aiyar N, Yue TL, Brown AJ, Morrison AD, Douglas SA. Johns DG, et al. Among authors: shabon u. Br J Pharmacol. 2007 Nov;152(5):825-31. doi: 10.1038/sj.bjp.0707419. Epub 2007 Aug 20. Br J Pharmacol. 2007. PMID: 17704827 Free PMC article.
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids.
Briscoe CP, Tadayyon M, Andrews JL, Benson WG, Chambers JK, Eilert MM, Ellis C, Elshourbagy NA, Goetz AS, Minnick DT, Murdock PR, Sauls HR Jr, Shabon U, Spinage LD, Strum JC, Szekeres PG, Tan KB, Way JM, Ignar DM, Wilson S, Muir AI. Briscoe CP, et al. Among authors: shabon u. J Biol Chem. 2003 Mar 28;278(13):11303-11. doi: 10.1074/jbc.M211495200. Epub 2002 Dec 19. J Biol Chem. 2003. PMID: 12496284 Free article.
Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor.
Elshourbagy NA, Ames RS, Fitzgerald LR, Foley JJ, Chambers JK, Szekeres PG, Evans NA, Schmidt DB, Buckley PT, Dytko GM, Murdock PR, Milligan G, Groarke DA, Tan KB, Shabon U, Nuthulaganti P, Wang DY, Wilson S, Bergsma DJ, Sarau HM. Elshourbagy NA, et al. Among authors: shabon u. J Biol Chem. 2000 Aug 25;275(34):25965-71. doi: 10.1074/jbc.M004515200. J Biol Chem. 2000. PMID: 10851242 Free article.
AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1.
Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CG, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harrison DC. Muir AI, et al. Among authors: shabon u. J Biol Chem. 2001 Aug 3;276(31):28969-75. doi: 10.1074/jbc.M102743200. Epub 2001 May 31. J Biol Chem. 2001. PMID: 11387329 Free article.
Localisation of NMU1R and NMU2R in human and rat central nervous system and effects of neuromedin-U following central administration in rats.
Gartlon J, Szekeres P, Pullen M, Sarau HM, Aiyar N, Shabon U, Michalovich D, Steplewski K, Ellis C, Elshourbagy N, Duxon M, Ashmeade TE, Harrison DC, Murdock P, Wilson S, Ennaceur A, Atkins A, Heidbreder C, Hagan JJ, Hunter AJ, Jones DN. Gartlon J, et al. Among authors: shabon u. Psychopharmacology (Berl). 2004 Dec;177(1-2):1-14. doi: 10.1007/s00213-004-1918-3. Epub 2004 Jun 16. Psychopharmacology (Berl). 2004. PMID: 15205870
11 results