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A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Pérez-Vargas J, Worrall LJ, Olmstead AD, Ton AT, Lee J, Villanueva I, Thompson CAH, Dudek S, Ennis S, Smith JR, Shapira T, De Guzman J, Gang S, Ban F, Vuckovic M, Bielecki M, Kovacic S, Kenward C, Hong CY, Gordon DG, Levett PN, Krajden M, Leduc R, Boudreault PL, Niikura M, Paetzel M, Young RN, Cherkasov A, Strynadka NCJ, Jean F. Pérez-Vargas J, et al. Among authors: shapira t. Emerg Microbes Infect. 2023 Dec;12(2):2246594. doi: 10.1080/22221751.2023.2246594. Emerg Microbes Infect. 2023. PMID: 37555275 Free PMC article.
The Role of 68 Ga-FAPI PET/CT in Breast Cancer Response Assessment and Follow-Up.
Eshet Y, Tau N, Levanon K, Bernstein-Molho R, Globus O, Itay A, Shapira T, Oedegaard C, Eifer M, Davidson T, Nidam M, Gal-Yam E, Domachevsky L. Eshet Y, et al. Among authors: shapira t. Clin Nucl Med. 2023 Aug 1;48(8):685-688. doi: 10.1097/RLU.0000000000004744. Epub 2023 Jun 17. Clin Nucl Med. 2023. PMID: 37339456
Corrigendum to "Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics" "Antiviral Research 209 (2023)/105484".
Perez-Vargas J, Shapira T, Olmstead AD, Villanueva I, Thompson CAH, Ennis S, Gao G, De Guzman J, Williams DE, Wang M, Chin A, Bautista-Sanchez D, Agafitei O, Levett P, Xie X, Nuzzo G, Freire VF, Quintana-Bulla JI, Bernardi DI, Gubiani JR, Suthiphasilp V, Raksat A, Meesakul P, Polbuppha I, Cheenpracha S, Jaidee W, Kanokmedhakul K, Yenjai C, Chaiyosang B, Teles HL, Manzo E, Fontana A, Leduc R, Boudreault PL, Berlinck RGS, Laphookhieo S, Kanokmedhakul S, Tietjen I, Cherkasov A, Krajden M, Nabi IR, Niikura M, Shi PY, Andersen RJ, Jean F. Perez-Vargas J, et al. Among authors: shapira t. Antiviral Res. 2023 May;213:105577. doi: 10.1016/j.antiviral.2023.105577. Epub 2023 Mar 30. Antiviral Res. 2023. PMID: 37002158 Free PMC article. No abstract available.
The Role of 68 Ga-FAPI PET/CT in Detection of Metastatic Lobular Breast Cancer.
Eshet Y, Tau N, Apter S, Nissan N, Levanon K, Bernstein-Molho R, Globus O, Itay A, Shapira T, Oedegaard C, Gorfine M, Eifer M, Davidson T, Gal-Yam E, Domachevsky L. Eshet Y, et al. Among authors: shapira t. Clin Nucl Med. 2023 Mar 1;48(3):228-232. doi: 10.1097/RLU.0000000000004540. Epub 2023 Jan 14. Clin Nucl Med. 2023. PMID: 36638243
SNAC for Enhanced Oral Bioavailability: An Updated Review.
Kommineni N, Sainaga Jyothi VGS, Butreddy A, Raju S, Shapira T, Khan W, Angsantikul P, Domb AJ. Kommineni N, et al. Among authors: shapira t. Pharm Res. 2023 Mar;40(3):633-650. doi: 10.1007/s11095-022-03459-9. Epub 2022 Dec 20. Pharm Res. 2023. PMID: 36539668 Review.
Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics.
Pérez-Vargas J, Shapira T, Olmstead AD, Villanueva I, Thompson CAH, Ennis S, Gao G, De Guzman J, Williams DE, Wang M, Chin A, Bautista-Sánchez D, Agafitei O, Levett P, Xie X, Nuzzo G, Freire VF, Quintana-Bulla JI, Bernardi DI, Gubiani JR, Suthiphasilp V, Raksat A, Meesakul P, Polbuppha I, Cheenpracha S, Jaidee W, Kanokmedhakul K, Yenjai C, Chaiyosang B, Teles HL, Manzo E, Fontana A, Leduc R, Boudreault PL, Berlinck RGS, Laphookhieo S, Kanokmedhakul S, Tietjen I, Cherkasov A, Krajden M, Nabi IR, Niikura M, Shi PY, Andersen RJ, Jean F. Pérez-Vargas J, et al. Among authors: shapira t. Antiviral Res. 2023 Jan;209:105484. doi: 10.1016/j.antiviral.2022.105484. Epub 2022 Dec 8. Antiviral Res. 2023. PMID: 36503013 Free PMC article.
A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic.
Shapira T, Monreal IA, Dion SP, Buchholz DW, Imbiakha B, Olmstead AD, Jager M, Désilets A, Gao G, Martins M, Vandal T, Thompson CAH, Chin A, Rees WD, Steiner T, Nabi IR, Marsault E, Sahler J, Diel DG, Van de Walle GR, August A, Whittaker GR, Boudreault PL, Leduc R, Aguilar HC, Jean F. Shapira T, et al. Nature. 2022 May;605(7909):340-348. doi: 10.1038/s41586-022-04661-w. Epub 2022 Mar 28. Nature. 2022. PMID: 35344983 Free PMC article.
46 results