Sharma V - Search Results

1

Mannose supplements induce embryonic lethality and blindness in phosphomannose isomerase hypomorphic mice.

Sharma V, Nayak J, DeRossi C, Charbono A, Ichikawa M, Ng BG, Grajales-Esquivel E, Srivastava A, Wang L, He P, Scott DA, Russell J, Contreras E, Guess CM, Krajewski S, Del Rio-Tsonis K, Freeze HH. Sharma V, et al. FASEB J. 2014 Apr;28(4):1854-69. doi: 10.1096/fj.13-245514. Epub 2014 Jan 13. FASEB J. 2014. PMID: 24421398 Free PMC article.

2

Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts.

Sharma V, Ichikawa M, He P, Scott DA, Bravo Y, Dahl R, Ng BG, Cosford ND, Freeze HH. Sharma V, et al. J Biol Chem. 2011 Nov 11;286(45):39431-8. doi: 10.1074/jbc.M111.285502. Epub 2011 Sep 26. J Biol Chem. 2011. PMID: 21949237 Free PMC article.

3

Mannose metabolism: more than meets the eye.

Sharma V, Ichikawa M, Freeze HH. Sharma V, et al. Biochem Biophys Res Commun. 2014 Oct 17;453(2):220-8. doi: 10.1016/j.bbrc.2014.06.021. Epub 2014 Jun 12. Biochem Biophys Res Commun. 2014. PMID: 24931670 Free PMC article. Review.

4

Metabolic manipulation of glycosylation disorders in humans and animal models.

Freeze HH, Sharma V. Freeze HH, et al. Among authors: sharma v. Semin Cell Dev Biol. 2010 Aug;21(6):655-62. doi: 10.1016/j.semcdb.2010.03.011. Epub 2010 Apr 2. Semin Cell Dev Biol. 2010. PMID: 20363348 Free PMC article. Review.

5

Identification of the first COG-CDG patient of Indian origin.

Ng BG, Sharma V, Sun L, Loh E, Hong W, Tay SK, Freeze HH. Ng BG, et al. Among authors: sharma v. Mol Genet Metab. 2011 Mar;102(3):364-7. doi: 10.1016/j.ymgme.2010.11.161. Epub 2010 Nov 24. Mol Genet Metab. 2011. PMID: 21185756 Free PMC article.

6

Mannose efflux from the cells: a potential source of mannose in blood.

Sharma V, Freeze HH. Sharma V, et al. J Biol Chem. 2011 Mar 25;286(12):10193-200. doi: 10.1074/jbc.M110.194241. Epub 2011 Jan 27. J Biol Chem. 2011. PMID: 21273394 Free PMC article.

7

Potent, selective, and orally available benzoisothiazolone phosphomannose isomerase inhibitors as probes for congenital disorder of glycosylation Ia.

Dahl R, Bravo Y, Sharma V, Ichikawa M, Dhanya RP, Hedrick M, Brown B, Rascon J, Vicchiarelli M, Mangravita-Novo A, Yang L, Stonich D, Su Y, Smith LH, Sergienko E, Freeze HH, Cosford ND. Dahl R, et al. Among authors: sharma v. J Med Chem. 2011 May 26;54(10):3661-8. doi: 10.1021/jm101401a. Epub 2011 May 3. J Med Chem. 2011. PMID: 21539312 Free PMC article.

8

Mannose Alters Gut Microbiome, Prevents Diet-Induced Obesity, and Improves Host Metabolism.

Sharma V, Smolin J, Nayak J, Ayala JE, Scott DA, Peterson SN, Freeze HH. Sharma V, et al. Cell Rep. 2018 Sep 18;24(12):3087-3098. doi: 10.1016/j.celrep.2018.08.064. Cell Rep. 2018. PMID: 30231992 Free PMC article.

9

A zebrafish model of congenital disorders of glycosylation with phosphomannose isomerase deficiency reveals an early opportunity for corrective mannose supplementation.

Chu J, Mir A, Gao N, Rosa S, Monson C, Sharma V, Steet R, Freeze HH, Lehrman MA, Sadler KC. Chu J, et al. Among authors: sharma v. Dis Model Mech. 2013 Jan;6(1):95-105. doi: 10.1242/dmm.010116. Epub 2012 Aug 16. Dis Model Mech. 2013. PMID: 22899857 Free PMC article.

10

COG8 deficiency causes new congenital disorder of glycosylation type IIh.

Kranz C, Ng BG, Sun L, Sharma V, Eklund EA, Miura Y, Ungar D, Lupashin V, Winkel RD, Cipollo JF, Costello CE, Loh E, Hong W, Freeze HH. Kranz C, et al. Among authors: sharma v. Hum Mol Genet. 2007 Apr 1;16(7):731-41. doi: 10.1093/hmg/ddm028. Epub 2007 Mar 1. Hum Mol Genet. 2007. PMID: 17331980

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