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The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies.
Ji H, Li D, Chen L, Shimamura T, Kobayashi S, McNamara K, Mahmood U, Mitchell A, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Kim W, Jänne PA, Shapiro GI, Tenen D, Johnson BE, Weissleder R, Sharpless NE, Wong KK. Ji H, et al. Among authors: sharpless ne. Cancer Cell. 2006 Jun;9(6):485-95. doi: 10.1016/j.ccr.2006.04.022. Epub 2006 May 25. Cancer Cell. 2006. PMID: 16730237 Free article.
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis.
Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Bachoo RM, et al. Among authors: sharpless ne. Cancer Cell. 2002 Apr;1(3):269-77. doi: 10.1016/s1535-6108(02)00046-6. Cancer Cell. 2002. PMID: 12086863 Free article.
p53: good cop/bad cop.
Sharpless NE, DePinho RA. Sharpless NE, et al. Cell. 2002 Jul 12;110(1):9-12. doi: 10.1016/s0092-8674(02)00818-8. Cell. 2002. PMID: 12150992 Free article. Review.
EGFR targeted therapy: view from biological standpoint.
Ji H, Sharpless NE, Wong KK. Ji H, et al. Among authors: sharpless ne. Cell Cycle. 2006 Sep;5(18):2072-6. doi: 10.4161/cc.5.18.3277. Epub 2006 Sep 15. Cell Cycle. 2006. PMID: 16969107 Review.
The regulation of INK4/ARF in cancer and aging.
Kim WY, Sharpless NE. Kim WY, et al. Among authors: sharpless ne. Cell. 2006 Oct 20;127(2):265-75. doi: 10.1016/j.cell.2006.10.003. Cell. 2006. PMID: 17055429 Free article. Review.
LKB1 modulates lung cancer differentiation and metastasis.
Ji H, Ramsey MR, Hayes DN, Fan C, McNamara K, Kozlowski P, Torrice C, Wu MC, Shimamura T, Perera SA, Liang MC, Cai D, Naumov GN, Bao L, Contreras CM, Li D, Chen L, Krishnamurthy J, Koivunen J, Chirieac LR, Padera RF, Bronson RT, Lindeman NI, Christiani DC, Lin X, Shapiro GI, Jänne PA, Johnson BE, Meyerson M, Kwiatkowski DJ, Castrillon DH, Bardeesy N, Sharpless NE, Wong KK. Ji H, et al. Among authors: sharpless ne. Nature. 2007 Aug 16;448(7155):807-10. doi: 10.1038/nature06030. Epub 2007 Aug 5. Nature. 2007. PMID: 17676035
VHL inactivation: a new road to senescence.
Kim WY, Sharpless NE. Kim WY, et al. Among authors: sharpless ne. Cancer Cell. 2008 Apr;13(4):295-7. doi: 10.1016/j.ccr.2008.03.012. Cancer Cell. 2008. PMID: 18394552 Free article.
194 results