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BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency.
Gupta M, Concepcion CP, Fahey CG, Keshishian H, Bhutkar A, Brainson CF, Sanchez-Rivera FJ, Pessina P, Kim JY, Simoneau A, Paschini M, Beytagh MC, Stanclift CR, Schenone M, Mani DR, Li C, Oh A, Li F, Hu H, Karatza A, Bronson RT, Shaw AT, Hata AN, Wong KK, Zou L, Carr SA, Jacks T, Kim CF. Gupta M, et al. Among authors: shaw at. Cancer Res. 2020 Sep 15;80(18):3841-3854. doi: 10.1158/0008-5472.CAN-20-1744. Epub 2020 Jul 20. Cancer Res. 2020. PMID: 32690724 Free PMC article.
Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.
Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, Bronson RT, Orkin SH, DePinho RA, Jacks T. Tuveson DA, et al. Among authors: shaw at. Cancer Cell. 2004 Apr;5(4):375-87. doi: 10.1016/s1535-6108(04)00085-6. Cancer Cell. 2004. PMID: 15093544 Free article.
Mouse models of human non-small-cell lung cancer: raising the bar.
Kim CF, Jackson EL, Kirsch DG, Grimm J, Shaw AT, Lane K, Kissil J, Olive KP, Sweet-Cordero A, Weissleder R, Jacks T. Kim CF, et al. Among authors: shaw at. Cold Spring Harb Symp Quant Biol. 2005;70:241-50. doi: 10.1101/sqb.2005.70.037. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869760 Review.
Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis.
Shaw AT, Meissner A, Dowdle JA, Crowley D, Magendantz M, Ouyang C, Parisi T, Rajagopal J, Blank LJ, Bronson RT, Stone JR, Tuveson DA, Jaenisch R, Jacks T. Shaw AT, et al. Genes Dev. 2007 Mar 15;21(6):694-707. doi: 10.1101/gad.1526207. Genes Dev. 2007. PMID: 17369402 Free PMC article.
Targeting anaplastic lymphoma kinase in lung cancer.
Shaw AT, Solomon B. Shaw AT, et al. Clin Cancer Res. 2011 Apr 15;17(8):2081-6. doi: 10.1158/1078-0432.CCR-10-1591. Epub 2011 Feb 2. Clin Cancer Res. 2011. PMID: 21288922 Review.
ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: an analysis of 1,683 patients with non-small cell lung cancer.
Gainor JF, Varghese AM, Ou SH, Kabraji S, Awad MM, Katayama R, Pawlak A, Mino-Kenudson M, Yeap BY, Riely GJ, Iafrate AJ, Arcila ME, Ladanyi M, Engelman JA, Dias-Santagata D, Shaw AT. Gainor JF, et al. Among authors: shaw at. Clin Cancer Res. 2013 Aug 1;19(15):4273-81. doi: 10.1158/1078-0432.CCR-13-0318. Epub 2013 May 31. Clin Cancer Res. 2013. PMID: 23729361 Free PMC article.
The new kid on the block: RET in lung cancer.
Gainor JF, Shaw AT. Gainor JF, et al. Among authors: shaw at. Cancer Discov. 2013 Jun;3(6):604-6. doi: 10.1158/2159-8290.CD-13-0174. Cancer Discov. 2013. PMID: 23749525
223 results