Shears SB - Search Results

1

Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP₇.

Riley AM, Wang H, Shears SB, Potter BVL. Riley AM, et al. Among authors: shears sb. Medchemcomm. 2019 Jun 7;10(7):1165-1172. doi: 10.1039/c9md00163h. eCollection 2019 Jul 1. Medchemcomm. 2019. PMID: 31391889 Free PMC article.

2

Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate.

Yang X, Rudolf M, Carew MA, Yoshida M, Nerreter V, Riley AM, Chung SK, Bruzik KS, Potter BV, Schultz C, Shears SB. Yang X, et al. Among authors: shears sb. J Biol Chem. 1999 Jul 2;274(27):18973-80. doi: 10.1074/jbc.274.27.18973. J Biol Chem. 1999. PMID: 10383396 Free article.

3

Synthesis and biological activity of D- and L-chiro-inositol 2,3,4,5-tetrakisphosphate: design of a novel and potent inhibitor of Ins(3,4,5,6)P4 1-kinase/Ins(1,3,4)P3 5/6-kinase.

Liu C, Riley AM, Yang X, Shears SB, Potter BV. Liu C, et al. Among authors: shears sb. J Med Chem. 2001 Aug 30;44(18):2984-9. doi: 10.1021/jm000553k. J Med Chem. 2001. PMID: 11520207

4

Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase.

Ho MW, Yang X, Carew MA, Zhang T, Hua L, Kwon YU, Chung SK, Adelt S, Vogel G, Riley AM, Potter BV, Shears SB. Ho MW, et al. Among authors: shears sb. Curr Biol. 2002 Mar 19;12(6):477-82. doi: 10.1016/s0960-9822(02)00713-3. Curr Biol. 2002. PMID: 11909533 Free article.

5

On the contribution of stereochemistry to human ITPK1 specificity: Ins(1,4,5,6)P4 is not a physiologic substrate.

Riley AM, Deleu S, Qian X, Mitchell J, Chung SK, Adelt S, Vogel G, Potter BV, Shears SB. Riley AM, et al. Among authors: shears sb. FEBS Lett. 2006 Jan 9;580(1):324-30. doi: 10.1016/j.febslet.2005.12.016. Epub 2005 Dec 19. FEBS Lett. 2006. PMID: 16376887 Free article.

6

scyllo-inositol pentakisphosphate as an analogue of myo-inositol 1,3,4,5,6-pentakisphosphate: chemical synthesis, physicochemistry and biological applications.

Riley AM, Trusselle M, Kuad P, Borkovec M, Cho J, Choi JH, Qian X, Shears SB, Spiess B, Potter BV. Riley AM, et al. Among authors: shears sb. Chembiochem. 2006 Jul;7(7):1114-22. doi: 10.1002/cbic.200600037. Chembiochem. 2006. PMID: 16755629 Free PMC article.

7

Diphosphoinositol polyphosphates: what are the mechanisms?

Shears SB, Gokhale NA, Wang H, Zaremba A. Shears SB, et al. Adv Enzyme Regul. 2011;51(1):13-25. doi: 10.1016/j.advenzreg.2010.09.008. Epub 2010 Oct 28. Adv Enzyme Regul. 2011. PMID: 21035493 Free PMC article. Review.

8

Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding.

Wang H, Falck JR, Hall TM, Shears SB. Wang H, et al. Among authors: shears sb. Nat Chem Biol. 2011 Nov 27;8(1):111-6. doi: 10.1038/nchembio.733. Nat Chem Biol. 2011. PMID: 22119861 Free PMC article.

9

Defining signal transduction by inositol phosphates.

Shears SB, Ganapathi SB, Gokhale NA, Schenk TM, Wang H, Weaver JD, Zaremba A, Zhou Y. Shears SB, et al. Subcell Biochem. 2012;59:389-412. doi: 10.1007/978-94-007-3015-1_13. Subcell Biochem. 2012. PMID: 22374098 Free PMC article. Review.

10

Activation of PLC by an endogenous cytokine (GBP) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1.

Zhou Y, Wu S, Wang H, Hayakawa Y, Bird GS, Shears SB. Zhou Y, et al. Among authors: shears sb. Biochem J. 2012 Dec 1;448(2):273-83. doi: 10.1042/BJ20120730. Biochem J. 2012. PMID: 22928859 Free PMC article.

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