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Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point.
Ndhlovu ZM, Kamya P, Mewalal N, Kløverpris HN, Nkosi T, Pretorius K, Laher F, Ogunshola F, Chopera D, Shekhar K, Ghebremichael M, Ismail N, Moodley A, Malik A, Leslie A, Goulder PJ, Buus S, Chakraborty A, Dong K, Ndung'u T, Walker BD. Ndhlovu ZM, et al. Among authors: shekhar k. Immunity. 2015 Sep 15;43(3):591-604. doi: 10.1016/j.immuni.2015.08.012. Epub 2015 Sep 8. Immunity. 2015. PMID: 26362266 Free PMC article.
Coordinate linkage of HIV evolution reveals regions of immunological vulnerability.
Dahirel V, Shekhar K, Pereyra F, Miura T, Artyomov M, Talsania S, Allen TM, Altfeld M, Carrington M, Irvine DJ, Walker BD, Chakraborty AK. Dahirel V, et al. Among authors: shekhar k. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11530-5. doi: 10.1073/pnas.1105315108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690407 Free PMC article.
Continuous immunotypes describe human immune variation and predict diverse responses.
Kaczorowski KJ, Shekhar K, Nkulikiyimfura D, Dekker CL, Maecker H, Davis MM, Chakraborty AK, Brodin P. Kaczorowski KJ, et al. Among authors: shekhar k. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6097-E6106. doi: 10.1073/pnas.1705065114. Epub 2017 Jul 10. Proc Natl Acad Sci U S A. 2017. PMID: 28696306 Free PMC article.
Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys.
Barouch DH, Whitney JB, Moldt B, Klein F, Oliveira TY, Liu J, Stephenson KE, Chang HW, Shekhar K, Gupta S, Nkolola JP, Seaman MS, Smith KM, Borducchi EN, Cabral C, Smith JY, Blackmore S, Sanisetty S, Perry JR, Beck M, Lewis MG, Rinaldi W, Chakraborty AK, Poignard P, Nussenzweig MC, Burton DR. Barouch DH, et al. Among authors: shekhar k. Nature. 2013 Nov 14;503(7475):224-8. doi: 10.1038/nature12744. Epub 2013 Oct 30. Nature. 2013. PMID: 24172905 Free PMC article.
Hydrophobic CDR3 residues promote the development of self-reactive T cells.
Stadinski BD, Shekhar K, Gómez-Touriño I, Jung J, Sasaki K, Sewell AK, Peakman M, Chakraborty AK, Huseby ES. Stadinski BD, et al. Among authors: shekhar k. Nat Immunol. 2016 Aug;17(8):946-55. doi: 10.1038/ni.3491. Epub 2016 Jun 27. Nat Immunol. 2016. PMID: 27348411 Free PMC article.
Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors.
Villani AC, Satija R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, Griesbeck M, Butler A, Zheng S, Lazo S, Jardine L, Dixon D, Stephenson E, Nilsson E, Grundberg I, McDonald D, Filby A, Li W, De Jager PL, Rozenblatt-Rosen O, Lane AA, Haniffa M, Regev A, Hacohen N. Villani AC, et al. Among authors: shekhar k. Science. 2017 Apr 21;356(6335):eaah4573. doi: 10.1126/science.aah4573. Science. 2017. PMID: 28428369 Free PMC article.
Single-Cell RNA Sequencing of Human T Cells.
Villani AC, Shekhar K. Villani AC, et al. Among authors: shekhar k. Methods Mol Biol. 2017;1514:203-239. doi: 10.1007/978-1-4939-6548-9_16. Methods Mol Biol. 2017. PMID: 27787803
89 results