Shoichet BK - Search Results

1

Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic Inference.

Pimentel-Elardo SM, Sørensen D, Ho L, Ziko M, Bueler SA, Lu S, Tao J, Moser A, Lee R, Agard D, Fairn G, Rubinstein JL, Shoichet BK, Nodwell JR. Pimentel-Elardo SM, et al. Among authors: shoichet bk. ACS Chem Biol. 2015 Nov 20;10(11):2616-23. doi: 10.1021/acschembio.5b00612. Epub 2015 Sep 18. ACS Chem Biol. 2015. PMID: 26352211 Free PMC article.

2

Molecular docking and ligand specificity in fragment-based inhibitor discovery.

Chen Y, Shoichet BK. Chen Y, et al. Among authors: shoichet bk. Nat Chem Biol. 2009 May;5(5):358-64. doi: 10.1038/nchembio.155. Epub 2009 Mar 22. Nat Chem Biol. 2009. PMID: 19305397 Free PMC article.

3

Quantifying biogenic bias in screening libraries.

Hert J, Irwin JJ, Laggner C, Keiser MJ, Shoichet BK. Hert J, et al. Among authors: shoichet bk. Nat Chem Biol. 2009 Jul;5(7):479-83. doi: 10.1038/nchembio.180. Epub 2009 May 31. Nat Chem Biol. 2009. PMID: 19483698 Free PMC article.

4

Ligand discovery from a dopamine D3 receptor homology model and crystal structure.

Carlsson J, Coleman RG, Setola V, Irwin JJ, Fan H, Schlessinger A, Sali A, Roth BL, Shoichet BK. Carlsson J, et al. Among authors: shoichet bk. Nat Chem Biol. 2011 Sep 18;7(11):769-78. doi: 10.1038/nchembio.662. Nat Chem Biol. 2011. PMID: 21926995 Free PMC article.

5

Chemical informatics and target identification in a zebrafish phenotypic screen.

Laggner C, Kokel D, Setola V, Tolia A, Lin H, Irwin JJ, Keiser MJ, Cheung CY, Minor DL Jr, Roth BL, Peterson RT, Shoichet BK. Laggner C, et al. Among authors: shoichet bk. Nat Chem Biol. 2011 Dec 18;8(2):144-6. doi: 10.1038/nchembio.732. Nat Chem Biol. 2011. PMID: 22179068 Free PMC article.

6

A chemical screen identifies class a g-protein coupled receptors as regulators of cilia.

Avasthi P, Marley A, Lin H, Gregori-Puigjane E, Shoichet BK, von Zastrow M, Marshall WF. Avasthi P, et al. Among authors: shoichet bk. ACS Chem Biol. 2012 May 18;7(5):911-9. doi: 10.1021/cb200349v. Epub 2012 Mar 8. ACS Chem Biol. 2012. PMID: 22375814 Free PMC article.

7

Colloidal aggregation affects the efficacy of anticancer drugs in cell culture.

Owen SC, Doak AK, Wassam P, Shoichet MS, Shoichet BK. Owen SC, et al. Among authors: shoichet bk, shoichet ms. ACS Chem Biol. 2012 Aug 17;7(8):1429-35. doi: 10.1021/cb300189b. Epub 2012 Jun 8. ACS Chem Biol. 2012. PMID: 22625864 Free PMC article.

8

Conformation guides molecular efficacy in docking screens of activated β-2 adrenergic G protein coupled receptor.

Weiss DR, Ahn S, Sassano MF, Kleist A, Zhu X, Strachan R, Roth BL, Lefkowitz RJ, Shoichet BK. Weiss DR, et al. Among authors: shoichet bk. ACS Chem Biol. 2013 May 17;8(5):1018-26. doi: 10.1021/cb400103f. Epub 2013 Mar 21. ACS Chem Biol. 2013. PMID: 23485065 Free PMC article.

9

Colloidal drug formulations can explain "bell-shaped" concentration-response curves.

Owen SC, Doak AK, Ganesh AN, Nedyalkova L, McLaughlin CK, Shoichet BK, Shoichet MS. Owen SC, et al. Among authors: shoichet bk, shoichet ms. ACS Chem Biol. 2014 Mar 21;9(3):777-84. doi: 10.1021/cb4007584. Epub 2014 Jan 15. ACS Chem Biol. 2014. PMID: 24397822 Free PMC article.

10

Drug discovery: follow your lead.

Shoichet BK. Shoichet BK. Nat Chem Biol. 2014 Apr;10(4):244-5. doi: 10.1038/nchembio.1484. Nat Chem Biol. 2014. PMID: 24643239 No abstract available.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

274 results

Search Page