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Discovery and functional characterization of a neomorphic PTEN mutation.
Costa HA, Leitner MG, Sos ML, Mavrantoni A, Rychkova A, Johnson JR, Newton BW, Yee MC, De La Vega FM, Ford JM, Krogan NJ, Shokat KM, Oliver D, Halaszovich CR, Bustamante CD. Costa HA, et al. Among authors: shokat km. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13976-81. doi: 10.1073/pnas.1422504112. Epub 2015 Oct 26. Proc Natl Acad Sci U S A. 2015. PMID: 26504226 Free PMC article.
A surface on the androgen receptor that allosterically regulates coactivator binding.
Estébanez-Perpiñá E, Arnold LA, Nguyen P, Rodrigues ED, Mar E, Bateman R, Pallai P, Shokat KM, Baxter JD, Guy RK, Webb P, Fletterick RJ. Estébanez-Perpiñá E, et al. Among authors: shokat km. Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16074-9. doi: 10.1073/pnas.0708036104. Epub 2007 Oct 2. Proc Natl Acad Sci U S A. 2007. PMID: 17911242 Free PMC article.
A complex-based reconstruction of the Saccharomyces cerevisiae interactome.
Wang H, Kakaradov B, Collins SR, Karotki L, Fiedler D, Shales M, Shokat KM, Walther TC, Krogan NJ, Koller D. Wang H, et al. Among authors: shokat km. Mol Cell Proteomics. 2009 Jun;8(6):1361-81. doi: 10.1074/mcp.M800490-MCP200. Epub 2009 Jan 27. Mol Cell Proteomics. 2009. PMID: 19176519 Free PMC article.
Functional organization of the S. cerevisiae phosphorylation network.
Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, Shokat KM, Krogan NJ. Fiedler D, et al. Among authors: shokat km. Cell. 2009 Mar 6;136(5):952-63. doi: 10.1016/j.cell.2008.12.039. Cell. 2009. PMID: 19269370 Free PMC article.
Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer.
Sos ML, Fischer S, Ullrich R, Peifer M, Heuckmann JM, Koker M, Heynck S, Stückrath I, Weiss J, Fischer F, Michel K, Goel A, Regales L, Politi KA, Perera S, Getlik M, Heukamp LC, Ansén S, Zander T, Beroukhim R, Kashkar H, Shokat KM, Sellers WR, Rauh D, Orr C, Hoeflich KP, Friedman L, Wong KK, Pao W, Thomas RK. Sos ML, et al. Among authors: shokat km. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18351-6. doi: 10.1073/pnas.0907325106. Epub 2009 Oct 5. Proc Natl Acad Sci U S A. 2009. PMID: 19805051 Free PMC article.
391 results