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Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy.
Laurila PP, Luan P, Wohlwend M, Zanou N, Crisol B, Imamura de Lima T, Goeminne LJE, Gallart-Ayala H, Shong M, Ivanisevic J, Place N, Auwerx J. Laurila PP, et al. Among authors: shong m. Sci Adv. 2022 Jan 28;8(4):eabh4423. doi: 10.1126/sciadv.abh4423. Epub 2022 Jan 28. Sci Adv. 2022. PMID: 35089797 Free PMC article.
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
Chung HK, Ryu D, Kim KS, Chang JY, Kim YK, Yi HS, Kang SG, Choi MJ, Lee SE, Jung SB, Ryu MJ, Kim SJ, Kweon GR, Kim H, Hwang JH, Lee CH, Lee SJ, Wall CE, Downes M, Evans RM, Auwerx J, Shong M. Chung HK, et al. Among authors: shong m. J Cell Biol. 2017 Jan 2;216(1):149-165. doi: 10.1083/jcb.201607110. Epub 2016 Dec 16. J Cell Biol. 2017. PMID: 27986797 Free PMC article.
Reduced oxidative capacity in macrophages results in systemic insulin resistance.
Jung SB, Choi MJ, Ryu D, Yi HS, Lee SE, Chang JY, Chung HK, Kim YK, Kang SG, Lee JH, Kim KS, Kim HJ, Kim CS, Lee CH, Williams RW, Kim H, Lee HK, Auwerx J, Shong M. Jung SB, et al. Among authors: shong m. Nat Commun. 2018 Apr 19;9(1):1551. doi: 10.1038/s41467-018-03998-z. Nat Commun. 2018. PMID: 29674655 Free PMC article.
Inhibition of SIRT7 overcomes sorafenib acquired resistance by suppressing ERK1/2 phosphorylation via the DDX3X-mediated NLRP3 inflammasome in hepatocellular carcinoma.
Kim Y, Jung KY, Kim YH, Xu P, Kang BE, Jo Y, Pandit N, Kwon J, Gariani K, Gariani J, Lee J, Verbeek J, Nam S, Bae SJ, Ha KT, Yi HS, Shong M, Kim KH, Kim D, Jung HJ, Lee CW, Kim KR, Schoonjans K, Auwerx J, Ryu D. Kim Y, et al. Among authors: shong m. Drug Resist Updat. 2024 Mar;73:101054. doi: 10.1016/j.drup.2024.101054. Epub 2024 Jan 17. Drug Resist Updat. 2024. PMID: 38277756 Free PMC article.
216 results