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Co-chaperone FKBP38 promotes HERG trafficking.
Walker VE, Atanasiu R, Lam H, Shrier A. Walker VE, et al. Among authors: shrier a. J Biol Chem. 2007 Aug 10;282(32):23509-16. doi: 10.1074/jbc.M701006200. Epub 2007 Jun 14. J Biol Chem. 2007. PMID: 17569659 Free article.
Hsp40 chaperones promote degradation of the HERG potassium channel.
Walker VE, Wong MJ, Atanasiu R, Hantouche C, Young JC, Shrier A. Walker VE, et al. Among authors: shrier a. J Biol Chem. 2010 Jan 29;285(5):3319-29. doi: 10.1074/jbc.M109.024000. Epub 2009 Nov 25. J Biol Chem. 2010. PMID: 19940115 Free PMC article.
N-myristoylation and Ca2+ binding of calcineurin B homologous protein CHP3 are required to enhance Na+/H+ exchanger NHE1 half-life and activity at the plasma membrane.
Zaun HC, Shrier A, Orlowski J. Zaun HC, et al. Among authors: shrier a. J Biol Chem. 2012 Oct 26;287(44):36883-95. doi: 10.1074/jbc.M112.394700. Epub 2012 Sep 14. J Biol Chem. 2012. PMID: 22984264 Free PMC article.
Previous work has shown that the heart-enriched isoform, CHP3, regulates the plasmalemmal Na(+)/H(+) exchanger NHE1 isoform by enhancing its rate of oligosaccharide maturation and exocytosis as well as its half-life and transport activity at the cell surface (Zaun, H. C., Shri
Previous work has shown that the heart-enriched isoform, CHP3, regulates the plasmalemmal Na(+)/H(+) exchanger NHE1 isoform by enhancing its …
hERG quality control and the long QT syndrome.
Foo B, Williamson B, Young JC, Lukacs G, Shrier A. Foo B, et al. Among authors: shrier a. J Physiol. 2016 May 1;594(9):2469-81. doi: 10.1113/JP270531. Epub 2016 Feb 9. J Physiol. 2016. PMID: 26718903 Free PMC article. Review.
118 results