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High-fat-diet-induced remission of diabetes in a subset of KATP -GOF insulin-secretory-deficient mice.
Diabetes Obes Metab. 2018 Nov;20(11):2574-2584. doi: 10.1111/dom.13423. Epub 2018 Jul 11.
Diabetes Obes Metab. 2018.
PMID: 29896801
Free PMC article.
SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human KATP-induced diabetes through mitigation of oxidative and ER stress.
Shyr ZA, Yan Z, Ustione A, Egan EM, Remedi MS.
Shyr ZA, et al.
PLoS One. 2022 Feb 18;17(2):e0258054. doi: 10.1371/journal.pone.0258054. eCollection 2022.
PLoS One. 2022.
PMID: 35180212
Free PMC article.
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Genetic Reduction of Glucose Metabolism Preserves Functional β-Cell Mass in KATP-Induced Neonatal Diabetes.
Yan Z, Fortunato M, Shyr ZA, Clark AL, Fuess M, Nichols CG, Remedi MS.
Yan Z, et al. Among authors: shyr za.
Diabetes. 2022 Jun 1;71(6):1233-1245. doi: 10.2337/db21-0992.
Diabetes. 2022.
PMID: 35294000
Free PMC article.
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The role of membrane excitability in pancreatic β-cell glucotoxicity.
Shyr ZA, Wang Z, York NW, Nichols CG, Remedi MS.
Shyr ZA, et al.
Sci Rep. 2019 May 6;9(1):6952. doi: 10.1038/s41598-019-43452-8.
Sci Rep. 2019.
PMID: 31061431
Free PMC article.
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Beta-cell excitability and excitability-driven diabetes in adult Zebrafish islets.
Emfinger CH, Lőrincz R, Wang Y, York NW, Singareddy SS, Ikle JM, Tryon RC, McClenaghan C, Shyr ZA, Huang Y, Reissaus CA, Meyer D, Piston DW, Hyrc K, Remedi MS, Nichols CG.
Emfinger CH, et al. Among authors: shyr za.
Physiol Rep. 2019 Jun;7(11):e14101. doi: 10.14814/phy2.14101.
Physiol Rep. 2019.
PMID: 31161721
Free PMC article.
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Alterations in pancreatic islet cell function in response to small bowel resection.
Courtney CM, Shyr ZA, Yan Z, Onufer EJ, Steinberger AE, Tecos ME, Barron LK, Guo J, Remedi MS, Warner BW.
Courtney CM, et al. Among authors: shyr za.
Am J Physiol Gastrointest Liver Physiol. 2020 Jul 1;319(1):G36-G42. doi: 10.1152/ajpgi.00282.2019. Epub 2020 May 28.
Am J Physiol Gastrointest Liver Physiol. 2020.
PMID: 32463335
Free PMC article.
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Drug combination therapy for emerging viral diseases.
Shyr ZA, Cheng YS, Lo DC, Zheng W.
Shyr ZA, et al.
Drug Discov Today. 2021 Oct;26(10):2367-2376. doi: 10.1016/j.drudis.2021.05.008. Epub 2021 May 21.
Drug Discov Today. 2021.
PMID: 34023496
Free PMC article.
Review.
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Drug Discovery Strategies for SARS-CoV-2.
Shyr ZA, Gorshkov K, Chen CZ, Zheng W.
Shyr ZA, et al.
J Pharmacol Exp Ther. 2020 Oct;375(1):127-138. doi: 10.1124/jpet.120.000123. Epub 2020 Jul 28.
J Pharmacol Exp Ther. 2020.
PMID: 32723801
Free PMC article.
Review.
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