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Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Baker DJ, Childs BG, Durik M, Wijers ME, Sieben CJ, Zhong J, Saltness RA, Jeganathan KB, Verzosa GC, Pezeshki A, Khazaie K, Miller JD, van Deursen JM. Baker DJ, et al. Among authors: sieben cj. Nature. 2016 Feb 11;530(7589):184-9. doi: 10.1038/nature16932. Epub 2016 Feb 3. Nature. 2016. PMID: 26840489 Free PMC article.
Two-Step Senescence-Focused Cancer Therapies.
Sieben CJ, Sturmlechner I, van de Sluis B, van Deursen JM. Sieben CJ, et al. Trends Cell Biol. 2018 Sep;28(9):723-737. doi: 10.1016/j.tcb.2018.04.006. Epub 2018 May 17. Trends Cell Biol. 2018. PMID: 29776716 Free PMC article. Review.
Cellular senescence in renal ageing and disease.
Sturmlechner I, Durik M, Sieben CJ, Baker DJ, van Deursen JM. Sturmlechner I, et al. Among authors: sieben cj. Nat Rev Nephrol. 2017 Feb;13(2):77-89. doi: 10.1038/nrneph.2016.183. Epub 2016 Dec 28. Nat Rev Nephrol. 2017. PMID: 28029153 Review.
12 results