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Computational protein design enables a novel one-carbon assimilation pathway.
Siegel JB, Smith AL, Poust S, Wargacki AJ, Bar-Even A, Louw C, Shen BW, Eiben CB, Tran HM, Noor E, Gallaher JL, Bale J, Yoshikuni Y, Gelb MH, Keasling JD, Stoddard BL, Lidstrom ME, Baker D. Siegel JB, et al. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3704-9. doi: 10.1073/pnas.1500545112. Epub 2015 Mar 9. Proc Natl Acad Sci U S A. 2015. PMID: 25775555 Free PMC article.
Computational design of an α-gliadin peptidase.
Gordon SR, Stanley EJ, Wolf S, Toland A, Wu SJ, Hadidi D, Mills JH, Baker D, Pultz IS, Siegel JB. Gordon SR, et al. Among authors: siegel jb. J Am Chem Soc. 2012 Dec 19;134(50):20513-20. doi: 10.1021/ja3094795. Epub 2012 Dec 5. J Am Chem Soc. 2012. PMID: 23153249 Free PMC article.
Improvement of a potential anthrax therapeutic by computational protein design.
Wu SJ, Eiben CB, Carra JH, Huang I, Zong D, Liu P, Wu CT, Nivala J, Dunbar J, Huber T, Senft J, Schokman R, Smith MD, Mills JH, Friedlander AM, Baker D, Siegel JB. Wu SJ, et al. Among authors: siegel jb. J Biol Chem. 2011 Sep 16;286(37):32586-92. doi: 10.1074/jbc.M111.251041. Epub 2011 Jul 18. J Biol Chem. 2011. PMID: 21768086 Free PMC article.
Expanding the product profile of a microbial alkane biosynthetic pathway.
Harger M, Zheng L, Moon A, Ager C, An JH, Choe C, Lai YL, Mo B, Zong D, Smith MD, Egbert RG, Mills JH, Baker D, Pultz IS, Siegel JB. Harger M, et al. Among authors: siegel jb. ACS Synth Biol. 2013 Jan 18;2(1):59-62. doi: 10.1021/sb300061x. Epub 2012 Sep 26. ACS Synth Biol. 2013. PMID: 23656326 Free PMC article.
109 results