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Evidence that MIG-6 is a tumor-suppressor gene.
Zhang YW, Staal B, Su Y, Swiatek P, Zhao P, Cao B, Resau J, Sigler R, Bronson R, Vande Woude GF. Zhang YW, et al. Among authors: sigler r. Oncogene. 2007 Jan 11;26(2):269-76. doi: 10.1038/sj.onc.1209790. Epub 2006 Jul 3. Oncogene. 2007. PMID: 16819504
Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer.
Graveel CR, DeGroot JD, Su Y, Koeman J, Dykema K, Leung S, Snider J, Davies SR, Swiatek PJ, Cottingham S, Watson MA, Ellis MJ, Sigler RE, Furge KA, Vande Woude GF. Graveel CR, et al. Among authors: sigler re. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12909-14. doi: 10.1073/pnas.0810403106. Epub 2009 Jun 30. Proc Natl Acad Sci U S A. 2009. PMID: 19567831 Free PMC article.
A highly invasive human glioblastoma pre-clinical model for testing therapeutics.
Xie Q, Thompson R, Hardy K, DeCamp L, Berghuis B, Sigler R, Knudsen B, Cottingham S, Zhao P, Dykema K, Cao B, Resau J, Hay R, Vande Woude GF. Xie Q, et al. Among authors: sigler r. J Transl Med. 2008 Dec 3;6:77. doi: 10.1186/1479-5876-6-77. J Transl Med. 2008. PMID: 19055779 Free PMC article.
Inactivation of Apc in the mouse prostate causes prostate carcinoma.
Bruxvoort KJ, Charbonneau HM, Giambernardi TA, Goolsby JC, Qian CN, Zylstra CR, Robinson DR, Roy-Burman P, Shaw AK, Buckner-Berghuis BD, Sigler RE, Resau JH, Sullivan R, Bushman W, Williams BO. Bruxvoort KJ, et al. Among authors: sigler re. Cancer Res. 2007 Mar 15;67(6):2490-6. doi: 10.1158/0008-5472.CAN-06-3028. Cancer Res. 2007. PMID: 17363566
T cell responses in mammalian diaphanous-related formin mDia1 knock-out mice.
Eisenmann KM, West RA, Hildebrand D, Kitchen SM, Peng J, Sigler R, Zhang J, Siminovitch KA, Alberts AS. Eisenmann KM, et al. Among authors: sigler r. J Biol Chem. 2007 Aug 24;282(34):25152-8. doi: 10.1074/jbc.M703243200. Epub 2007 Jun 26. J Biol Chem. 2007. PMID: 17595162 Free article.
Essential role of beta-catenin in postnatal bone acquisition.
Holmen SL, Zylstra CR, Mukherjee A, Sigler RE, Faugere MC, Bouxsein ML, Deng L, Clemens TL, Williams BO. Holmen SL, et al. Among authors: sigler re. J Biol Chem. 2005 Jun 3;280(22):21162-8. doi: 10.1074/jbc.M501900200. Epub 2005 Mar 31. J Biol Chem. 2005. PMID: 15802266 Free article.
88 results