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Page 1
Opportunities for improving animal welfare in rodent models of epilepsy and seizures.
Lidster K, Jefferys JG, Blümcke I, Crunelli V, Flecknell P, Frenguelli BG, Gray WP, Kaminski R, Pitkänen A, Ragan I, Shah M, Simonato M, Trevelyan A, Volk H, Walker M, Yates N, Prescott MJ. Lidster K, et al. Among authors: simonato m. J Neurosci Methods. 2016 Feb 15;260:2-25. doi: 10.1016/j.jneumeth.2015.09.007. Epub 2015 Sep 12. J Neurosci Methods. 2016. PMID: 26376175 Free article. Review.
Identification of new epilepsy treatments: issues in preclinical methodology.
Galanopoulou AS, Buckmaster PS, Staley KJ, Moshé SL, Perucca E, Engel J Jr, Löscher W, Noebels JL, Pitkänen A, Stables J, White HS, O'Brien TJ, Simonato M; American Epilepsy Society Basic Science Committee And The International League Against Epilepsy Working Group On Recommendations For Preclinical Epilepsy Drug Discovery. Galanopoulou AS, et al. Among authors: simonato m. Epilepsia. 2012 Mar;53(3):571-82. doi: 10.1111/j.1528-1167.2011.03391.x. Epub 2012 Jan 31. Epilepsia. 2012. PMID: 22292566 Free PMC article. Review.
Finding a better drug for epilepsy: antiepileptogenesis targets.
Kobow K, Auvin S, Jensen F, Löscher W, Mody I, Potschka H, Prince D, Sierra A, Simonato M, Pitkänen A, Nehlig A, Rho JM. Kobow K, et al. Among authors: simonato m. Epilepsia. 2012 Nov;53(11):1868-76. doi: 10.1111/j.1528-1167.2012.03716.x. Epub 2012 Oct 12. Epilepsia. 2012. PMID: 23061663 Free PMC article. Review.
The challenge and promise of anti-epileptic therapy development in animal models.
Simonato M, Brooks-Kayal AR, Engel J Jr, Galanopoulou AS, Jensen FE, Moshé SL, O'Brien TJ, Pitkanen A, Wilcox KS, French JA. Simonato M, et al. Lancet Neurol. 2014 Sep;13(9):949-60. doi: 10.1016/S1474-4422(14)70076-6. Epub 2014 Aug 10. Lancet Neurol. 2014. PMID: 25127174 Free PMC article. Review.
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus.
Johnson MR, Behmoaras J, Bottolo L, Krishnan ML, Pernhorst K, Santoscoy PLM, Rossetti T, Speed D, Srivastava PK, Chadeau-Hyam M, Hajji N, Dabrowska A, Rotival M, Razzaghi B, Kovac S, Wanisch K, Grillo FW, Slaviero A, Langley SR, Shkura K, Roncon P, De T, Mattheisen M, Niehusmann P, O'Brien TJ, Petrovski S, von Lehe M, Hoffmann P, Eriksson J, Coffey AJ, Cichon S, Walker M, Simonato M, Danis B, Mazzuferi M, Foerch P, Schoch S, De Paola V, Kaminski RM, Cunliffe VT, Becker AJ, Petretto E. Johnson MR, et al. Among authors: simonato m. Nat Commun. 2015 Jan 23;6:6031. doi: 10.1038/ncomms7031. Nat Commun. 2015. PMID: 25615886 Free PMC article.
Advances in the development of biomarkers for epilepsy.
Pitkänen A, Löscher W, Vezzani A, Becker AJ, Simonato M, Lukasiuk K, Gröhn O, Bankstahl JP, Friedman A, Aronica E, Gorter JA, Ravizza T, Sisodiya SM, Kokaia M, Beck H. Pitkänen A, et al. Among authors: simonato m. Lancet Neurol. 2016 Jul;15(8):843-856. doi: 10.1016/S1474-4422(16)00112-5. Lancet Neurol. 2016. PMID: 27302363 Review.
Common data elements and data management: Remedy to cure underpowered preclinical studies.
Lapinlampi N, Melin E, Aronica E, Bankstahl JP, Becker A, Bernard C, Gorter JA, Gröhn O, Lipsanen A, Lukasiuk K, Löscher W, Paananen J, Ravizza T, Roncon P, Simonato M, Vezzani A, Kokaia M, Pitkänen A. Lapinlampi N, et al. Among authors: simonato m. Epilepsy Res. 2017 Jan;129:87-90. doi: 10.1016/j.eplepsyres.2016.11.010. Epub 2016 Nov 22. Epilepsy Res. 2017. PMID: 28038337
306 results