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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1979 1
1980 2
1983 2
1985 1
1990 1
1994 1
1997 1
1999 1
2000 2
2003 1
2004 1
2006 1
2007 1
2008 2
2009 4
2010 8
2011 4
2012 4
2013 6
2014 3
2015 1
2017 2
2018 2
2019 3
2020 3
2021 4
2022 3
2023 4
2024 2

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56 results

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Page 1
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.
Simpson DS, Pang J, Weir A, Kong IY, Fritsch M, Rashidi M, Cooney JP, Davidson KC, Speir M, Djajawi TM, Hughes S, Mackiewicz L, Dayton M, Anderton H, Doerflinger M, Deng Y, Huang AS, Conos SA, Tye H, Chow SH, Rahman A, Norton RS, Naderer T, Nicholson SE, Burgio G, Man SM, Groom JR, Herold MJ, Hawkins ED, Lawlor KE, Strasser A, Silke J, Pellegrini M, Kashkar H, Feltham R, Vince JE. Simpson DS, et al. Immunity. 2022 Mar 8;55(3):423-441.e9. doi: 10.1016/j.immuni.2022.01.003. Epub 2022 Feb 8. Immunity. 2022. PMID: 35139355 Free PMC article.
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency.
Hughes SA, Lin M, Weir A, Huang B, Xiong L, Chua NK, Pang J, Santavanond JP, Tixeira R, Doerflinger M, Deng Y, Yu CH, Silke N, Conos SA, Frank D, Simpson DS, Murphy JM, Lawlor KE, Pearson JS, Silke J, Pellegrini M, Herold MJ, Poon IKH, Masters SL, Li M, Tang Q, Zhang Y, Rashidi M, Geng L, Vince JE. Hughes SA, et al. Among authors: simpson ds. EMBO J. 2023 Mar 1;42(5):e110468. doi: 10.15252/embj.2021110468. Epub 2023 Jan 17. EMBO J. 2023. PMID: 36647737 Free PMC article.
Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells.
Wang Z, Burigotto M, Ghetti S, Vaillant F, Tan T, Capaldo BD, Palmieri M, Hirokawa Y, Tai L, Simpson DS, Chang C, Huang AS, Lieschke E, Diepstraten ST, Kaloni D, Riffkin C, Huang DCS, Li Wai Suen CSN, Garnham AL, Gibbs P, Visvader JE, Sieber OM, Herold MJ, Fava LL, Kelly GL, Strasser A. Wang Z, et al. Among authors: simpson ds. Cancer Discov. 2024 Feb 8;14(2):362-379. doi: 10.1158/2159-8290.CD-23-0402. Cancer Discov. 2024. PMID: 37877779 Free PMC article.
Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response.
Weerasinghe H, Simm C, Djajawi TM, Tedja I, Lo TL, Simpson DS, Shasha D, Mizrahi N, Olivier FAB, Speir M, Lawlor KE, Ben-Ami R, Traven A. Weerasinghe H, et al. Among authors: simpson ds. Cell Rep. 2023 May 30;42(5):112522. doi: 10.1016/j.celrep.2023.112522. Epub 2023 May 18. Cell Rep. 2023. PMID: 37204928 Free article.
A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation.
Speir M, Tye H, Gottschalk TA, Simpson DS, Djajawi TM, Deo P, Ambrose RL, Conos SA, Emery J, Abraham G, Pascoe A, Hughes SA, Weir A, Hawkins ED, Kong I, Herold MJ, Pearson JS, Lalaoui N, Naderer T, Vince JE, Lawlor KE. Speir M, et al. Among authors: simpson ds. EMBO Rep. 2023 Nov 6;24(11):e56865. doi: 10.15252/embr.202356865. Epub 2023 Oct 17. EMBO Rep. 2023. PMID: 37846472 Free PMC article.
Specific NLRP3 Inhibition Protects Against Diabetes-Associated Atherosclerosis.
Sharma A, Choi JSY, Stefanovic N, Al-Sharea A, Simpson DS, Mukhamedova N, Jandeleit-Dahm K, Murphy AJ, Sviridov D, Vince JE, Ritchie RH, de Haan JB. Sharma A, et al. Among authors: simpson ds. Diabetes. 2021 Mar;70(3):772-787. doi: 10.2337/db20-0357. Epub 2020 Dec 15. Diabetes. 2021. PMID: 33323396
56 results