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Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Locally Advanced Head and Neck Carcinoma: NRG Oncology Radiation Therapy Oncology Group 0522.
Truong MT, Zhang Q, Rosenthal DI, List M, Axelrod R, Sherman E, Weber R, Nguyen-Tân PF, El-Naggar A, Konski A, Galvin J, Schwartz D, Trotti A, Silverman C, Singh A, Godette K, Bonner JA, Jones CU, Garden AS, Shenouda G, Matthiesen C, Le QT, Bruner D. Truong MT, et al. Among authors: singh a. Int J Radiat Oncol Biol Phys. 2017 Mar 15;97(4):687-699. doi: 10.1016/j.ijrobp.2016.08.003. Epub 2016 Aug 12. Int J Radiat Oncol Biol Phys. 2017. PMID: 27727066 Free PMC article. Clinical Trial.
The addition of continuous infusion 5-FU to preoperative radiation therapy increases tumor response, leading to increased sphincter preservation in locally advanced rectal cancer.
Crane CH, Skibber JM, Birnbaum EH, Feig BW, Singh AK, Delclos ME, Lin EH, Fleshman JW, Thames HD, Kodner IJ, Lockett MA, Picus J, Phan T, Chandra A, Janjan NA, Read TE, Myerson RJ. Crane CH, et al. Among authors: singh ak. Int J Radiat Oncol Biol Phys. 2003 Sep 1;57(1):84-9. doi: 10.1016/s0360-3016(03)00532-7. Int J Radiat Oncol Biol Phys. 2003. PMID: 12909219
Intrarectal amifostine suspension may protect against acute proctitis during radiation therapy for prostate cancer: a pilot study.
Singh AK, Ménard C, Guion P, Simone NL, Smith S, Crouse NS, Godette DJ, Cooley-Zgela T, Sciuto LC, Coleman J, Pinto P, Albert PS, Camphausen K, Coleman CN. Singh AK, et al. Int J Radiat Oncol Biol Phys. 2006 Jul 15;65(4):1008-13. doi: 10.1016/j.ijrobp.2006.02.030. Epub 2006 May 26. Int J Radiat Oncol Biol Phys. 2006. PMID: 16730138
Intrarectal amifostine during external beam radiation therapy for prostate cancer produces significant improvements in Quality of Life measured by EPIC score.
Simone NL, Ménard C, Soule BP, Albert PS, Guion P, Smith S, Godette D, Crouse NS, Sciuto LC, Cooley-Zgela T, Camphausen K, Coleman CN, Singh AK. Simone NL, et al. Int J Radiat Oncol Biol Phys. 2008 Jan 1;70(1):90-5. doi: 10.1016/j.ijrobp.2007.05.057. Epub 2007 Sep 12. Int J Radiat Oncol Biol Phys. 2008. PMID: 17855015 Free PMC article.
Radiation treatment interruptions greater than one week and low hemoglobin levels (12 g/dL) are predictors of local regional failure after definitive concurrent chemotherapy and intensity-modulated radiation therapy for squamous cell carcinoma of the head and neck.
McCloskey SA, Jaggernauth W, Rigual NR, Hicks WL Jr, Popat SR, Sullivan M, Mashtare TL Jr, Khan MK, Loree TR, Singh AK. McCloskey SA, et al. Among authors: singh ak. Am J Clin Oncol. 2009 Dec;32(6):587-91. doi: 10.1097/COC.0b013e3181967dd0. Am J Clin Oncol. 2009. PMID: 19581794
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