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Page 1
An MHC-defined primate model reveals significant rejection of bone marrow after mixed chimerism induction despite full MHC matching.
Larsen CP, Page A, Linzie KH, Russell M, Deane T, Stempora L, Strobert E, Penedo MC, Ward T, Wiseman R, O'Connor D, Miller W, Sen S, Singh K, Kean LS. Larsen CP, et al. Among authors: singh k. Am J Transplant. 2010 Nov;10(11):2396-409. doi: 10.1111/j.1600-6143.2010.03272.x. Epub 2010 Sep 17. Am J Transplant. 2010. PMID: 20849552 Free PMC article.
CD40 blockade combines with CTLA4Ig and sirolimus to produce mixed chimerism in an MHC-defined rhesus macaque transplant model.
Page A, Srinivasan S, Singh K, Russell M, Hamby K, Deane T, Sen S, Stempora L, Leopardi F, Price AA, Strobert E, Reimann KA, Kirk AD, Larsen CP, Kean LS. Page A, et al. Among authors: singh k. Am J Transplant. 2012 Jan;12(1):115-25. doi: 10.1111/j.1600-6143.2011.03737.x. Epub 2011 Sep 19. Am J Transplant. 2012. PMID: 21929643 Free PMC article.
Evidence for kidney rejection after combined bone marrow and renal transplantation despite ongoing whole-blood chimerism in rhesus macaques.
Ramakrishnan SK, Page A, Farris AB 3rd, Singh K, Leopardi F, Hamby K, Sen S, Polnett A, Deane T, Song M, Stempora L, Strobert E, Kirk AD, Larsen CP, Kean LS. Ramakrishnan SK, et al. Among authors: singh k. Am J Transplant. 2012 Jul;12(7):1755-64. doi: 10.1111/j.1600-6143.2012.04045.x. Epub 2012 May 29. Am J Transplant. 2012. PMID: 22642491 Free PMC article.
The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques.
Zheng HB, Watkins B, Tkachev V, Yu S, Tran D, Furlan S, Zeleski K, Singh K, Hamby K, Hotchkiss C, Lane J, Gumber S, Adams AB, Cendales L, Kirk AD, Kaur A, Blazar BR, Larsen CP, Kean LS. Zheng HB, et al. Among authors: singh k. Am J Transplant. 2017 Mar;17(3):657-670. doi: 10.1111/ajt.14006. Epub 2016 Sep 19. Am J Transplant. 2017. PMID: 27500470 Free PMC article.
GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression.
Miller WP, Srinivasan S, Panoskaltsis-Mortari A, Singh K, Sen S, Hamby K, Deane T, Stempora L, Beus J, Turner A, Wheeler C, Anderson DC, Sharma P, Garcia A, Strobert E, Elder E, Crocker I, Crenshaw T, Penedo MC, Ward T, Song M, Horan J, Larsen CP, Blazar BR, Kean LS. Miller WP, et al. Among authors: singh k. Blood. 2010 Dec 9;116(24):5403-18. doi: 10.1182/blood-2010-06-289272. Epub 2010 Sep 10. Blood. 2010. PMID: 20833977 Free PMC article.
Significant mobilization of both conventional and regulatory T cells with AMD3100.
Kean LS, Sen S, Onabajo O, Singh K, Robertson J, Stempora L, Bonifacino AC, Metzger ME, Promislow DE, Mattapallil JJ, Donahue RE. Kean LS, et al. Among authors: singh k. Blood. 2011 Dec 15;118(25):6580-90. doi: 10.1182/blood-2011-06-359331. Epub 2011 Oct 11. Blood. 2011. PMID: 21989987 Free PMC article.
Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease.
Hippen KL, Watkins B, Tkachev V, Lemire AM, Lehnen C, Riddle MJ, Singh K, Panoskaltsis-Mortari A, Vanhove B, Tolar J, Kean LS, Blazar BR. Hippen KL, et al. Among authors: singh k. Transplantation. 2016 Dec;100(12):2630-2639. doi: 10.1097/TP.0000000000001465. Transplantation. 2016. PMID: 27861291 Free PMC article.
9,384 results