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Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features.
Singh RK, Vikram P, Makker J, Jabeen T, Sharma S, Dey S, Kaur P, Srinivasan A, Singh TP. Singh RK, et al. Among authors: singh tp. Biochemistry. 2003 Oct 14;42(40):11701-6. doi: 10.1021/bi035076x. Biochemistry. 2003. PMID: 14529280
Detection of native peptides as potent inhibitors of enzymes. Crystal structure of the complex formed between treated bovine alpha-chymotrypsin and an autocatalytically produced fragment, IIe-Val-Asn-Gly-Glu-Glu-Ala-Val-Pro-Gly-Ser-Trp-Pro-Trp, at 2.2 angstroms resolution.
Singh N, Jabeen T, Sharma S, Roy I, Gupta MN, Bilgrami S, Somvanshi RK, Dey S, Perbandt M, Betzel C, Srinivasan A, Singh TP. Singh N, et al. Among authors: singh tp. FEBS J. 2005 Jan;272(2):562-72. doi: 10.1111/j.1742-4658.2004.04499.x. FEBS J. 2005. PMID: 15654893 Free article.
Structure of the zinc-induced heterodimer of two calcium-free isoforms of phospholipase A2 from Naja naja sagittifera at 2.7 angstroms resolution.
Jabeen T, Sharma S, Singh N, Singh RK, Verma AK, Paramasivam M, Srinivasan A, Singh TP. Jabeen T, et al. Among authors: singh n, singh rk, singh tp. Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):302-8. doi: 10.1107/S0907444904033165. Epub 2005 Feb 24. Acta Crystallogr D Biol Crystallogr. 2005. PMID: 15735340
700 results