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5-Formylcytosine does not change the global structure of DNA.
Hardwick JS, Ptchelkine D, El-Sagheer AH, Tear I, Singleton D, Phillips SEV, Lane AN, Brown T. Hardwick JS, et al. Among authors: singleton d. Nat Struct Mol Biol. 2017 Jun;24(6):544-552. doi: 10.1038/nsmb.3411. Epub 2017 May 15. Nat Struct Mol Biol. 2017. PMID: 28504696 Free PMC article.
An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.
Baker YR, Thorpe C, Chen J, Poller LM, Cox L, Kumar P, Lim WF, Lie L, McClorey G, Epple S, Singleton D, McDonough MA, Hardwick JS, Christensen KE, Wood MJA, Hall JP, El-Sagheer AH, Brown T. Baker YR, et al. Among authors: singleton d. Nat Commun. 2022 Jul 12;13(1):4036. doi: 10.1038/s41467-022-31636-2. Nat Commun. 2022. PMID: 35821218 Free PMC article.
AT-CuAAC Synthesis of Mechanically Interlocked Oligonucleotides.
Acevedo-Jake A, Ball AT, Galli M, Kukwikila M, Denis M, Singleton DG, Tavassoli A, Goldup SM. Acevedo-Jake A, et al. J Am Chem Soc. 2020 Apr 1;142(13):5985-5990. doi: 10.1021/jacs.0c01670. Epub 2020 Mar 20. J Am Chem Soc. 2020. PMID: 32155338 Free PMC article.
277 results