Sippl W - Search Results

1

Ubiquitin-specific proteases as cancer drug targets.

Sippl W, Collura V, Colland F. Sippl W, et al. Future Oncol. 2011 May;7(5):619-32. doi: 10.2217/fon.11.39. Future Oncol. 2011. PMID: 21568678 Review.

2

Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells.

Colland F, Formstecher E, Jacq X, Reverdy C, Planquette C, Conrath S, Trouplin V, Bianchi J, Aushev VN, Camonis J, Calabrese A, Borg-Capra C, Sippl W, Collura V, Boissy G, Rain JC, Guedat P, Delansorne R, Daviet L. Colland F, et al. Among authors: sippl w. Mol Cancer Ther. 2009 Aug;8(8):2286-95. doi: 10.1158/1535-7163.MCT-09-0097. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671755

3

Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme.

Reverdy C, Conrath S, Lopez R, Planquette C, Atmanene C, Collura V, Harpon J, Battaglia V, Vivat V, Sippl W, Colland F. Reverdy C, et al. Among authors: sippl w. Chem Biol. 2012 Apr 20;19(4):467-77. doi: 10.1016/j.chembiol.2012.02.007. Chem Biol. 2012. PMID: 22520753

4

The role of histone demethylases in cancer therapy.

Hoffmann I, Roatsch M, Schmitt ML, Carlino L, Pippel M, Sippl W, Jung M. Hoffmann I, et al. Among authors: sippl w. Mol Oncol. 2012 Dec;6(6):683-703. doi: 10.1016/j.molonc.2012.07.004. Epub 2012 Aug 7. Mol Oncol. 2012. PMID: 22902149 Free PMC article. Review.

5

Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo.

Gajer JM, Furdas SD, Gründer A, Gothwal M, Heinicke U, Keller K, Colland F, Fulda S, Pahl HL, Fichtner I, Sippl W, Jung M. Gajer JM, et al. Among authors: sippl w. Oncogenesis. 2015 Feb 9;4(2):e137. doi: 10.1038/oncsis.2014.51. Oncogenesis. 2015. PMID: 25664930 Free PMC article.

6

[Development of histone deacetylase inhibitors Potent active ingredients especially in cancer].

Heinke R, Sippl W. Heinke R, et al. Among authors: sippl w. Pharm Unserer Zeit. 2010 May;39(3):183-9. doi: 10.1002/pauz.201000364. Pharm Unserer Zeit. 2010. PMID: 20425772 Review. German. No abstract available.

7

Inhibitors to understand molecular mechanisms of NAD(+)-dependent deacetylases (sirtuins).

Lawson M, Uciechowska U, Schemies J, Rumpf T, Jung M, Sippl W. Lawson M, et al. Among authors: sippl w. Biochim Biophys Acta. 2010 Oct-Dec;1799(10-12):726-39. doi: 10.1016/j.bbagrm.2010.06.003. Epub 2010 Jun 23. Biochim Biophys Acta. 2010. PMID: 20601279 Review.

8

Computer- and structure-based lead design for epigenetic targets.

Heinke R, Carlino L, Kannan S, Jung M, Sippl W. Heinke R, et al. Among authors: sippl w. Bioorg Med Chem. 2011 Jun 15;19(12):3605-15. doi: 10.1016/j.bmc.2011.01.029. Epub 2011 Jan 22. Bioorg Med Chem. 2011. PMID: 21316248

9

Current trends in epigenetic drug discovery.

Stolfa DA, Einsle O, Sippl W, Jung M. Stolfa DA, et al. Among authors: sippl w. Future Med Chem. 2012 Oct;4(16):2029-37. doi: 10.4155/fmc.12.144. Future Med Chem. 2012. PMID: 23157236

10

Targeting histone deacetylase 8 as a therapeutic approach to cancer and neurodegenerative diseases.

Chakrabarti A, Melesina J, Kolbinger FR, Oehme I, Senger J, Witt O, Sippl W, Jung M. Chakrabarti A, et al. Among authors: sippl w. Future Med Chem. 2016 Sep;8(13):1609-34. doi: 10.4155/fmc-2016-0117. Epub 2016 Aug 30. Future Med Chem. 2016. PMID: 27572818 Free article. Review.

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