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Year Number of Results
2015 1
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2017 3
2018 2
2019 1
2020 3
2021 2
2022 3
2023 1
2024 1

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Page 1
NEDD4 degrades TUSC2 to promote glioblastoma progression.
Rimkus TK, Arrigo AB, Zhu D, Carpenter RL, Sirkisoon S, Doheny D, Regua AT, Wong GL, Manore S, Wagner C, Lin HK, Jin G, Ruiz J, Chan M, Debinski W, Lo HW. Rimkus TK, et al. Among authors: sirkisoon s. Cancer Lett. 2022 Apr 10;531:124-135. doi: 10.1016/j.canlet.2022.01.029. Epub 2022 Feb 12. Cancer Lett. 2022. PMID: 35167936 Free PMC article.
EGFR and HER2 signaling in breast cancer brain metastasis.
Sirkisoon SR, Carpenter RL, Rimkus T, Miller L, Metheny-Barlow L, Lo HW. Sirkisoon SR, et al. Front Biosci (Elite Ed). 2016 Jan 1;8(2):245-63. doi: 10.2741/E765. Front Biosci (Elite Ed). 2016. PMID: 26709660 Free PMC article.
Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases.
Sirkisoon SR, Wong GL, Aguayo NR, Doheny DL, Zhu D, Regua AT, Arrigo A, Manore SG, Wagner C, Thomas A, Singh R, Xing F, Jin G, Watabe K, Lo HW. Sirkisoon SR, et al. Cancer Lett. 2022 Aug 1;540:215726. doi: 10.1016/j.canlet.2022.215726. Epub 2022 May 16. Cancer Lett. 2022. PMID: 35589002 Free PMC article.
Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis.
Doheny D, Sirkisoon S, Carpenter RL, Aguayo NR, Regua AT, Anguelov M, Manore SG, Arrigo A, Jalboush SA, Wong GL, Yu Y, Wagner CJ, Chan M, Ruiz J, Thomas A, Strowd R, Lin J, Lo HW. Doheny D, et al. Among authors: sirkisoon s. Oncogene. 2020 Oct;39(42):6589-6605. doi: 10.1038/s41388-020-01454-1. Epub 2020 Sep 14. Oncogene. 2020. PMID: 32929154 Free PMC article.
Cardiovascular impact of near complete estrogen deprivation in premenopausal women with breast cancer: The CROWN study.
Thomas A, O'Connell NS, Douglas E, Hatcher S, Park CJ, Dent S, Ansley K, Klem I, Bansal R, Westbrook K, Hundley WG, Bottinor W, Hackney MH, Richardson KM, Sirkisoon SR, D'Agostino RB Jr, Jordan JH. Thomas A, et al. Among authors: sirkisoon sr. Am Heart J. 2024 Jan;267:33-43. doi: 10.1016/j.ahj.2023.10.007. Epub 2023 Oct 26. Am Heart J. 2024. PMID: 37890547
An FDA-Approved Antifungal, Ketoconazole, and Its Novel Derivative Suppress tGLI1-Mediated Breast Cancer Brain Metastasis by Inhibiting the DNA-Binding Activity of Brain Metastasis-Promoting Transcription Factor tGLI1.
Doheny D, Manore S, Sirkisoon SR, Zhu D, Aguayo NR, Harrison A, Najjar M, Anguelov M, Cox AO, Furdui CM, Watabe K, Hollis T, Thomas A, Strowd R, Lo HW. Doheny D, et al. Among authors: sirkisoon sr. Cancers (Basel). 2022 Aug 31;14(17):4256. doi: 10.3390/cancers14174256. Cancers (Basel). 2022. PMID: 36077791 Free PMC article.
TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment.
Sirkisoon SR, Carpenter RL, Rimkus T, Doheny D, Zhu D, Aguayo NR, Xing F, Chan M, Ruiz J, Metheny-Barlow LJ, Strowd R, Lin J, Regua AT, Arrigo A, Anguelov M, Pasche B, Debinski W, Watabe K, Lo HW. Sirkisoon SR, et al. Oncogene. 2020 Jan;39(1):64-78. doi: 10.1038/s41388-019-0959-3. Epub 2019 Aug 28. Oncogene. 2020. PMID: 31462709 Free PMC article.
16 results