Siuciak JA - Search Results

1

CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of antipsychotic activity.

Siuciak JA, Chapin DS, McCarthy SA, Guanowsky V, Brown J, Chiang P, Marala R, Patterson T, Seymour PA, Swick A, Iredale PA. Siuciak JA, et al. Neuropharmacology. 2007 Feb;52(2):279-90. doi: 10.1016/j.neuropharm.2006.07.024. Epub 2006 Sep 1. Neuropharmacology. 2007. PMID: 16949622

2

Behavioral and neurochemical characterization of mice deficient in the phosphodiesterase-1B (PDE1B) enzyme.

Siuciak JA, McCarthy SA, Chapin DS, Reed TM, Vorhees CV, Repaske DR. Siuciak JA, et al. Neuropharmacology. 2007 Jul;53(1):113-24. doi: 10.1016/j.neuropharm.2007.04.009. Epub 2007 Apr 29. Neuropharmacology. 2007. PMID: 17559891

3

Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: evidence for altered striatal function.

Siuciak JA, McCarthy SA, Chapin DS, Fujiwara RA, James LC, Williams RD, Stock JL, McNeish JD, Strick CA, Menniti FS, Schmidt CJ. Siuciak JA, et al. Neuropharmacology. 2006 Aug;51(2):374-85. doi: 10.1016/j.neuropharm.2006.01.012. Epub 2006 Jun 12. Neuropharmacology. 2006. PMID: 16769090

4

Inhibition of the striatum-enriched phosphodiesterase PDE10A: a novel approach to the treatment of psychosis.

Siuciak JA, Chapin DS, Harms JF, Lebel LA, McCarthy SA, Chambers L, Shrikhande A, Wong S, Menniti FS, Schmidt CJ. Siuciak JA, et al. Neuropharmacology. 2006 Aug;51(2):386-96. doi: 10.1016/j.neuropharm.2006.04.013. Epub 2006 Jun 15. Neuropharmacology. 2006. PMID: 16780899

5

Antipsychotic profile of rolipram: efficacy in rats and reduced sensitivity in mice deficient in the phosphodiesterase-4B (PDE4B) enzyme.

Siuciak JA, Chapin DS, McCarthy SA, Martin AN. Siuciak JA, et al. Psychopharmacology (Berl). 2007 Jun;192(3):415-24. doi: 10.1007/s00213-007-0727-x. Epub 2007 Mar 2. Psychopharmacology (Berl). 2007. PMID: 17333137

6

Behavioral and neurochemical characterization of mice deficient in the phosphodiesterase-4B (PDE4B) enzyme.

Siuciak JA, McCarthy SA, Chapin DS, Martin AN. Siuciak JA, et al. Psychopharmacology (Berl). 2008 Mar;197(1):115-26. doi: 10.1007/s00213-007-1014-6. Epub 2007 Dec 1. Psychopharmacology (Berl). 2008. PMID: 18060387

7

Behavioral characterization of mice deficient in the phosphodiesterase-10A (PDE10A) enzyme on a C57/Bl6N congenic background.

Siuciak JA, McCarthy SA, Chapin DS, Martin AN, Harms JF, Schmidt CJ. Siuciak JA, et al. Neuropharmacology. 2008 Feb;54(2):417-27. doi: 10.1016/j.neuropharm.2007.10.009. Epub 2007 Dec 3. Neuropharmacology. 2008. PMID: 18061215

8

Disruption of the neurokinin-3 receptor (NK3) in mice leads to cognitive deficits.

Siuciak JA, McCarthy SA, Martin AN, Chapin DS, Stock J, Nadeau DM, Kantesaria S, Bryce-Pritt D, McLean S. Siuciak JA, et al. Psychopharmacology (Berl). 2007 Oct;194(2):185-95. doi: 10.1007/s00213-007-0828-6. Epub 2007 Jun 10. Psychopharmacology (Berl). 2007. PMID: 17558564

9

Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia.

Schmidt CJ, Chapin DS, Cianfrogna J, Corman ML, Hajos M, Harms JF, Hoffman WE, Lebel LA, McCarthy SA, Nelson FR, Proulx-LaFrance C, Majchrzak MJ, Ramirez AD, Schmidt K, Seymour PA, Siuciak JA, Tingley FD 3rd, Williams RD, Verhoest PR, Menniti FS. Schmidt CJ, et al. Among authors: siuciak ja. J Pharmacol Exp Ther. 2008 May;325(2):681-90. doi: 10.1124/jpet.107.132910. Epub 2008 Feb 20. J Pharmacol Exp Ther. 2008. PMID: 18287214

10

1-[(1-methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 positive allosteric modulators for the treatment of psychosis.

Zhang L, Brodney MA, Candler J, Doran AC, Duplantier AJ, Efremov IV, Evrard E, Kraus K, Ganong AH, Haas JA, Hanks AN, Jenza K, Lazzaro JT, Maklad N, McCarthy SA, Qian W, Rogers BN, Rottas MD, Schmidt CJ, Siuciak JA, Tingley FD 3rd, Zhang AQ. Zhang L, et al. Among authors: siuciak ja. J Med Chem. 2011 Mar 24;54(6):1724-39. doi: 10.1021/jm101414h. Epub 2011 Mar 2. J Med Chem. 2011. PMID: 21366332

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