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Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein.
Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH. Nakamura K, et al. Among authors: skibinski g. J Biol Chem. 2011 Jun 10;286(23):20710-26. doi: 10.1074/jbc.M110.213538. Epub 2011 Apr 13. J Biol Chem. 2011. PMID: 21489994 Free PMC article.
iPS cells in the study of PD molecular pathogenesis.
Cobb MM, Ravisankar A, Skibinski G, Finkbeiner S. Cobb MM, et al. Among authors: skibinski g. Cell Tissue Res. 2018 Jul;373(1):61-77. doi: 10.1007/s00441-017-2749-y. Epub 2017 Dec 12. Cell Tissue Res. 2018. PMID: 29234887 Free PMC article. Review.
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease.
Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, Callaway K, Anderson JP, Jobling MF, Buell AK, Yednock TA, Knowles TP, Vendruscolo M, Christodoulou J, Dobson CM, Schenk D, McConlogue L. Tóth G, et al. Among authors: skibinski g. PLoS One. 2014 Feb 14;9(2):e87133. doi: 10.1371/journal.pone.0087133. eCollection 2014. PLoS One. 2014. PMID: 24551051 Free PMC article.
Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the α-synuclein (SNCA) gene associated with Parkinson's disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007).
Novak G, Finkbeiner S, Skibinski G, Skupin A. Novak G, et al. Among authors: skibinski g. Stem Cell Res. 2021 Dec;57:102600. doi: 10.1016/j.scr.2021.102600. Epub 2021 Nov 22. Stem Cell Res. 2021. PMID: 34826737 Free PMC article.
95 results