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ARID1A Regulates Transcription and the Epigenetic Landscape via POLE and DMAP1 while ARID1A Deficiency or Pharmacological Inhibition Sensitizes Germ Cell Tumor Cells to ATR Inhibition.
Kurz L, Miklyaeva A, Skowron MA, Overbeck N, Poschmann G, Becker T, Eul K, Kurz T, Schönberger S, Calaminus G, Stühler K, Dykhuizen E, Albers P, Nettersheim D. Kurz L, et al. Among authors: skowron ma. Cancers (Basel). 2020 Apr 7;12(4):905. doi: 10.3390/cancers12040905. Cancers (Basel). 2020. PMID: 32272809 Free PMC article.
CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms.
Skowron MA, Vermeulen M, Winkelhausen A, Becker TK, Bremmer F, Petzsch P, Schönberger S, Calaminus G, Köhrer K, Albers P, Nettersheim D. Skowron MA, et al. Br J Cancer. 2020 Aug;123(3):378-391. doi: 10.1038/s41416-020-0891-x. Epub 2020 May 18. Br J Cancer. 2020. PMID: 32418994 Free PMC article.
37 results