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Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations.
Koskimäki J, Zhang D, Li Y, Saadat L, Moore T, Lightle R, Polster SP, Carrión-Penagos J, Lyne SB, Zeineddine HA, Shi C, Shenkar R, Romanos S, Avner K, Srinath A, Shen L, Detter MR, Snellings D, Cao Y, Lopez-Ramirez MA, Fonseca G, Tang AT, Faber P, Andrade J, Ginsberg M, Kahn ML, Marchuk DA, Girard R, Awad IA. Koskimäki J, et al. Among authors: snellings d. Acta Neuropathol Commun. 2019 Aug 19;7(1):132. doi: 10.1186/s40478-019-0789-0. Acta Neuropathol Commun. 2019. PMID: 31426861 Free PMC article.
PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Ren AA, Snellings DA, Su YS, Hong CC, Castro M, Tang AT, Detter MR, Hobson N, Girard R, Romanos S, Lightle R, Moore T, Shenkar R, Benavides C, Beaman MM, Müller-Fielitz H, Chen M, Mericko P, Yang J, Sung DC, Lawton MT, Ruppert JM, Schwaninger M, Körbelin J, Potente M, Awad IA, Marchuk DA, Kahn ML. Ren AA, et al. Among authors: snellings da. Nature. 2021 Jun;594(7862):271-276. doi: 10.1038/s41586-021-03562-8. Epub 2021 Apr 28. Nature. 2021. PMID: 33910229 Free PMC article.
Cerebral Cavernous Malformation: From Mechanism to Therapy.
Snellings DA, Hong CC, Ren AA, Lopez-Ramirez MA, Girard R, Srinath A, Marchuk DA, Ginsberg MH, Awad IA, Kahn ML. Snellings DA, et al. Circ Res. 2021 Jun 25;129(1):195-215. doi: 10.1161/CIRCRESAHA.121.318174. Epub 2021 Jun 24. Circ Res. 2021. PMID: 34166073 Free PMC article. Review.
Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease.
Romanos SG, Srinath A, Li Y, Xie B, Chen C, Li Y, Moore T, Bi D, Sone JY, Lightle R, Hobson N, Zhang D, Koskimäki J, Shen L, McCurdy S, Lai CC, Stadnik A, Piedad K, Carrión-Penagos J, Shkoukani A, Snellings D, Shenkar R, Sulakhe D, Ji Y, Lopez-Ramirez MA, Kahn ML, Marchuk DA, Ginsberg MH, Girard R, Awad IA. Romanos SG, et al. Among authors: snellings d. Transl Stroke Res. 2023 Aug;14(4):513-529. doi: 10.1007/s12975-022-01050-3. Epub 2022 Jun 17. Transl Stroke Res. 2023. PMID: 35715588
Adaptive sequence divergence forged new neurodevelopmental enhancers in humans.
Mangan RJ, Alsina FC, Mosti F, Sotelo-Fonseca JE, Snellings DA, Au EH, Carvalho J, Sathyan L, Johnson GD, Reddy TE, Silver DL, Lowe CB. Mangan RJ, et al. Among authors: snellings da. Cell. 2022 Nov 23;185(24):4587-4603.e23. doi: 10.1016/j.cell.2022.10.016. Cell. 2022. PMID: 36423581 Free PMC article.
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