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Page 1
Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood-Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2.
J Am Chem Soc. 2022 Sep 21;144(37):16930-16952. doi: 10.1021/jacs.2c05499. Epub 2022 Aug 25.
J Am Chem Soc. 2022.
PMID: 36007011
Free PMC article.
New forms of old drugs: improving without changing.
Domingos S, André V, Quaresma S, Martins IC, Minas da Piedade MF, Duarte MT.
Domingos S, et al.
J Pharm Pharmacol. 2015 Jun;67(6):830-46. doi: 10.1111/jphp.12384. Epub 2015 Feb 3.
J Pharm Pharmacol. 2015.
PMID: 25648101
Review.
Item in Clipboard
Targeting leucine-rich repeat kinase 2 (LRRK2) for the treatment of Parkinson's disease.
Domingos S, Duarte T, Saraiva L, Guedes RC, Moreira R.
Domingos S, et al.
Future Med Chem. 2019 Aug;11(15):1953-1977. doi: 10.4155/fmc-2018-0484.
Future Med Chem. 2019.
PMID: 31517532
Review.
Item in Clipboard
The Lisbon Supramolecular Green Story: Mechanochemistry towards New Forms of Pharmaceuticals.
Ferreira da Silva JL, Minas da Piedade MF, André V, Domingos S, Martins ICB, Duarte MT.
Ferreira da Silva JL, et al. Among authors: domingos s.
Molecules. 2020 Jun 11;25(11):2705. doi: 10.3390/molecules25112705.
Molecules. 2020.
PMID: 32545242
Free PMC article.
Review.
Item in Clipboard
Enhanced cytotoxicity of prenylated chalcone against tumour cells via disruption of the p53-MDM2 interaction.
Leão M, Soares J, Gomes S, Raimundo L, Ramos H, Bessa C, Queiroz G, Domingos S, Pinto M, Inga A, Cidade H, Saraiva L.
Leão M, et al. Among authors: domingos s.
Life Sci. 2015 Dec 1;142:60-5. doi: 10.1016/j.lfs.2015.10.015. Epub 2015 Oct 21.
Life Sci. 2015.
PMID: 26475964
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