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Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle.
Sonsalla G, Malpartida AB, Riedemann T, Gusic M, Rusha E, Bulli G, Najas S, Janjic A, Hersbach BA, Smialowski P, Drukker M, Enard W, Prehn JHM, Prokisch H, Götz M, Masserdotti G. Sonsalla G, et al. Among authors: najas s. Neuron. 2024 Apr 3;112(7):1117-1132.e9. doi: 10.1016/j.neuron.2023.12.020. Epub 2024 Jan 23. Neuron. 2024. PMID: 38266647 Free PMC article.
Trnp1 organizes diverse nuclear membrane-less compartments in neural stem cells.
Esgleas M, Falk S, Forné I, Thiry M, Najas S, Zhang S, Mas-Sanchez A, Geerlof A, Niessing D, Wang Z, Imhof A, Götz M. Esgleas M, et al. Among authors: najas s. EMBO J. 2020 Aug 17;39(16):e103373. doi: 10.15252/embj.2019103373. Epub 2020 Jul 6. EMBO J. 2020. PMID: 32627867 Free PMC article.
Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome.
Arranz J, Balducci E, Arató K, Sánchez-Elexpuru G, Najas S, Parras A, Rebollo E, Pijuan I, Erb I, Verde G, Sahun I, Barallobre MJ, Lucas JJ, Sánchez MP, de la Luna S, Arbonés ML. Arranz J, et al. Among authors: najas s. Neurobiol Dis. 2019 Jul;127:210-222. doi: 10.1016/j.nbd.2019.02.022. Epub 2019 Mar 1. Neurobiol Dis. 2019. PMID: 30831192 Free PMC article.
DYRK1A: a master regulatory protein controlling brain growth.
Guedj F, Pereira PL, Najas S, Barallobre MJ, Chabert C, Souchet B, Sebrie C, Verney C, Herault Y, Arbones M, Delabar JM. Guedj F, et al. Among authors: najas s. Neurobiol Dis. 2012 Apr;46(1):190-203. doi: 10.1016/j.nbd.2012.01.007. Epub 2012 Jan 26. Neurobiol Dis. 2012. PMID: 22293606
TUNAR lncRNA Encodes a Microprotein that Regulates Neural Differentiation and Neurite Formation by Modulating Calcium Dynamics.
Senís E, Esgleas M, Najas S, Jiménez-Sábado V, Bertani C, Giménez-Alejandre M, Escriche A, Ruiz-Orera J, Hergueta-Redondo M, Jiménez M, Giralt A, Nuciforo P, Albà MM, Peinado H, Del Toro D, Hove-Madsen L, Götz M, Abad M. Senís E, et al. Among authors: najas s. Front Cell Dev Biol. 2021 Dec 31;9:747667. doi: 10.3389/fcell.2021.747667. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 35036403 Free PMC article.