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Reactive astrogliosis causes the development of spontaneous seizures.
Robel S, Buckingham SC, Boni JL, Campbell SL, Danbolt NC, Riedemann T, Sutor B, Sontheimer H. Robel S, et al. Among authors: sontheimer h. J Neurosci. 2015 Feb 25;35(8):3330-45. doi: 10.1523/JNEUROSCI.1574-14.2015. J Neurosci. 2015. PMID: 25716834 Free PMC article.
Human glioma cells induce hyperexcitability in cortical networks.
Campbell SL, Buckingham SC, Sontheimer H. Campbell SL, et al. Among authors: sontheimer h. Epilepsia. 2012 Aug;53(8):1360-70. doi: 10.1111/j.1528-1167.2012.03557.x. Epub 2012 Jun 18. Epilepsia. 2012. PMID: 22709330 Free PMC article.
Glia as drivers of abnormal neuronal activity.
Robel S, Sontheimer H. Robel S, et al. Among authors: sontheimer h. Nat Neurosci. 2016 Jan;19(1):28-33. doi: 10.1038/nn.4184. Nat Neurosci. 2016. PMID: 26713746 Free PMC article. Review.
A neurocentric perspective on glioma invasion.
Cuddapah VA, Robel S, Watkins S, Sontheimer H. Cuddapah VA, et al. Among authors: sontheimer h. Nat Rev Neurosci. 2014 Jul;15(7):455-65. doi: 10.1038/nrn3765. Nat Rev Neurosci. 2014. PMID: 24946761 Free PMC article. Review.
SLC7A11 expression is associated with seizures and predicts poor survival in patients with malignant glioma.
Robert SM, Buckingham SC, Campbell SL, Robel S, Holt KT, Ogunrinu-Babarinde T, Warren PP, White DM, Reid MA, Eschbacher JM, Berens ME, Lahti AC, Nabors LB, Sontheimer H. Robert SM, et al. Among authors: sontheimer h. Sci Transl Med. 2015 May 27;7(289):289ra86. doi: 10.1126/scitranslmed.aaa8103. Sci Transl Med. 2015. PMID: 26019222 Free PMC article.
Sulfasalazine decreases astrogliosis-mediated seizure burden.
Alcoreza O, Jagarlamudi S, Savoia A, Campbell SL, Sontheimer H. Alcoreza O, et al. Among authors: sontheimer h. Epilepsia. 2022 Apr;63(4):844-854. doi: 10.1111/epi.17178. Epub 2022 Feb 7. Epilepsia. 2022. PMID: 35132640 Free PMC article.
215 results