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Page 1
Mitochondrial dysfunction in cell senescence and aging.
Miwa S, Kashyap S, Chini E, von Zglinicki T. Miwa S, et al. Among authors: kashyap s. J Clin Invest. 2022 Jul 1;132(13):e158447. doi: 10.1172/JCI158447. J Clin Invest. 2022. PMID: 35775483 Free PMC article. Review.
Evolving concepts in NAD+ metabolism.
Chini CCS, Zeidler JD, Kashyap S, Warner G, Chini EN. Chini CCS, et al. Among authors: kashyap s. Cell Metab. 2021 Jun 1;33(6):1076-1087. doi: 10.1016/j.cmet.2021.04.003. Epub 2021 Apr 29. Cell Metab. 2021. PMID: 33930322 Free PMC article. Review.
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels.
Chini CCS, Peclat TR, Warner GM, Kashyap S, Espindola-Netto JM, de Oliveira GC, Gomez LS, Hogan KA, Tarragó MG, Puranik AS, Agorrody G, Thompson KL, Dang K, Clarke S, Childs BG, Kanamori KS, Witte MA, Vidal P, Kirkland AL, De Cecco M, Chellappa K, McReynolds MR, Jankowski C, Tchkonia T, Kirkland JL, Sedivy JM, van Deursen JM, Baker DJ, van Schooten W, Rabinowitz JD, Baur JA, Chini EN. Chini CCS, et al. Among authors: kashyap s. Nat Metab. 2020 Nov;2(11):1284-1304. doi: 10.1038/s42255-020-00298-z. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199925 Free PMC article.
A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease.
Ramalingam H, Kashyap S, Cobo-Stark P, Flaten A, Chang CM, Hajarnis S, Hein KZ, Lika J, Warner GM, Espindola-Netto JM, Kumar A, Kanchwala M, Xing C, Chini EN, Patel V. Ramalingam H, et al. Among authors: kashyap s. Cell Metab. 2021 Jun 1;33(6):1234-1247.e7. doi: 10.1016/j.cmet.2021.03.024. Epub 2021 Apr 13. Cell Metab. 2021. PMID: 33852874 Free PMC article.
Implications of the NADase CD38 in COVID pathophysiology.
Zeidler JD, Kashyap S, Hogan KA, Chini EN. Zeidler JD, et al. Among authors: kashyap s. Physiol Rev. 2022 Jan 1;102(1):339-341. doi: 10.1152/physrev.00007.2021. Epub 2021 Sep 8. Physiol Rev. 2022. PMID: 34494892 Free PMC article. Review.
CD38-NADase is a new major contributor to Duchenne muscular dystrophic phenotype.
de Zélicourt A, Fayssoil A, Dakouane-Giudicelli M, De Jesus I, Karoui A, Zarrouki F, Lefebvre F, Mansart A, Launay JM, Piquereau J, Tarragó MG, Bonay M, Forand A, Moog S, Piétri-Rouxel F, Brisebard E, Chini CCS, Kashyap S, Fogarty MJ, Sieck GC, Mericskay M, Chini EN, Gomez AM, Cancela JM, de la Porte S. de Zélicourt A, et al. Among authors: kashyap s. EMBO Mol Med. 2022 May 9;14(5):e12860. doi: 10.15252/emmm.202012860. Epub 2022 Mar 17. EMBO Mol Med. 2022. PMID: 35298089 Free PMC article.
The CD38 glycohydrolase and the NAD sink: implications for pathological conditions.
Zeidler JD, Hogan KA, Agorrody G, Peclat TR, Kashyap S, Kanamori KS, Gomez LS, Mazdeh DZ, Warner GM, Thompson KL, Chini CCS, Chini EN. Zeidler JD, et al. Among authors: kashyap s. Am J Physiol Cell Physiol. 2022 Mar 1;322(3):C521-C545. doi: 10.1152/ajpcell.00451.2021. Epub 2022 Feb 9. Am J Physiol Cell Physiol. 2022. PMID: 35138178 Free PMC article. Review.
Endogenous metabolism in endothelial and immune cells generates most of the tissue vitamin B3 (nicotinamide).
Zeidler JD, Chini CCS, Kanamori KS, Kashyap S, Espindola-Netto JM, Thompson K, Warner G, Cabral FS, Peclat TR, Gomez LS, Lopez SA, Wandersee MK, Schoon RA, Reid K, Menzies K, Beckedorff F, Reid JM, Brachs S, Meyer RG, Meyer-Ficca ML, Chini EN. Zeidler JD, et al. Among authors: kashyap s. iScience. 2022 Oct 23;25(11):105431. doi: 10.1016/j.isci.2022.105431. eCollection 2022 Nov 18. iScience. 2022. PMID: 36388973 Free PMC article.
19 results