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The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway.
Spagnol V, Oliveira CAB, Randle SJ, Passos PMS, Correia CRSTB, Simaroli NB, Oliveira JS, Mevissen TET, Medeiros AC, Gomes MD, Komander D, Laman H, Teixeira FR. Spagnol V, et al. Biochim Biophys Acta Gen Subj. 2021 Jan;1865(1):129754. doi: 10.1016/j.bbagen.2020.129754. Epub 2020 Sep 30. Biochim Biophys Acta Gen Subj. 2021. PMID: 33010352 Free PMC article.
New insights on human Hsp70-escort protein 1: Chaperone activity, interaction with liposomes, cellular localizations and HSPA's self-assemblies remodeling.
Dores-Silva PR, Kiraly VTR, Moritz MNO, Serrão VHB, Dos Passos PMS, Spagnol V, Teixeira FR, Gava LM, Cauvi DM, Ramos CHI, De Maio A, Borges JC. Dores-Silva PR, et al. Among authors: spagnol v. Int J Biol Macromol. 2021 Jul 1;182:772-784. doi: 10.1016/j.ijbiomac.2021.04.048. Epub 2021 Apr 17. Int J Biol Macromol. 2021. PMID: 33857516