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Loss-Function Learning for Digital Tissue Deconvolution.
Görtler F, Schön M, Simeth J, Solbrig S, Wettig T, Oefner PJ, Spang R, Altenbuchinger M. Görtler F, et al. Among authors: spang r. J Comput Biol. 2020 Mar;27(3):342-355. doi: 10.1089/cmb.2019.0462. Epub 2020 Jan 29. J Comput Biol. 2020. PMID: 31995401
DTD: An R Package for Digital Tissue Deconvolution.
Schön M, Simeth J, Heinrich P, Görtler F, Solbrig S, Wettig T, Oefner PJ, Altenbuchinger M, Spang R. Schön M, et al. Among authors: spang r. J Comput Biol. 2020 Mar;27(3):386-389. doi: 10.1089/cmb.2019.0469. Epub 2020 Jan 29. J Comput Biol. 2020. PMID: 31995409 Free PMC article.
Modelling cancer progression using Mutual Hazard Networks.
Schill R, Solbrig S, Wettig T, Spang R. Schill R, et al. Among authors: spang r. Bioinformatics. 2020 Jan 1;36(1):241-249. doi: 10.1093/bioinformatics/btz513. Bioinformatics. 2020. PMID: 31250881 Free PMC article.
Reference point insensitive molecular data analysis.
Altenbuchinger M, Rehberg T, Zacharias HU, Stämmler F, Dettmer K, Weber D, Hiergeist A, Gessner A, Holler E, Oefner PJ, Spang R. Altenbuchinger M, et al. Among authors: spang r. Bioinformatics. 2017 Jan 15;33(2):219-226. doi: 10.1093/bioinformatics/btw598. Epub 2016 Sep 15. Bioinformatics. 2017. PMID: 27634945
Moreover, we describe a novel coordinate descent based algorithm to fit zero-sum elastic nets. AVAILABILITY AND IMPLEMENTATION: The R-package "zeroSum" can be downloaded at https://github.com/rehbergT/zeroSum Moreover, we provide all R-scripts and data used to produ …
Moreover, we describe a novel coordinate descent based algorithm to fit zero-sum elastic nets. AVAILABILITY AND IMPLEMENTATION: The R …
Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma.
Engelmann JC, Amann T, Ott-Rötzer B, Nützel M, Reinders Y, Reinders J, Thasler WE, Kristl T, Teufel A, Huber CG, Oefner PJ, Spang R, Hellerbrand C. Engelmann JC, et al. Among authors: spang r. PLoS Comput Biol. 2015 May 28;11(5):e1004293. doi: 10.1371/journal.pcbi.1004293. eCollection 2015 May. PLoS Comput Biol. 2015. PMID: 26020769 Free PMC article.
Scale-Invariant Biomarker Discovery in Urine and Plasma Metabolite Fingerprints.
Zacharias HU, Rehberg T, Mehrl S, Richtmann D, Wettig T, Oefner PJ, Spang R, Gronwald W, Altenbuchinger M. Zacharias HU, et al. Among authors: spang r. J Proteome Res. 2017 Oct 6;16(10):3596-3605. doi: 10.1021/acs.jproteome.7b00325. Epub 2017 Sep 7. J Proteome Res. 2017. PMID: 28825821
A multi-source data integration approach reveals novel associations between metabolites and renal outcomes in the German Chronic Kidney Disease study.
Altenbuchinger M, Zacharias HU, Solbrig S, Schäfer A, Büyüközkan M, Schultheiß UT, Kotsis F, Köttgen A, Spang R, Oefner PJ, Krumsiek J, Gronwald W. Altenbuchinger M, et al. Among authors: spang r. Sci Rep. 2019 Sep 27;9(1):13954. doi: 10.1038/s41598-019-50346-2. Sci Rep. 2019. PMID: 31562371 Free PMC article.
164 results