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Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia.
Rutten MGS, Lei Y, Hoogerland JH, Bloks VW, Yang H, Bos T, Krishnamurthy KA, Bleeker A, Koster MH, Thomas RE, Wolters JC, van den Bos H, Mithieux G, Rajas F, Mardinoglu A, Spierings DCJ, de Bruin A, van de Sluis B, Oosterveer MH. Rutten MGS, et al. Among authors: spierings dcj. Cancer Metab. 2023 Apr 21;11(1):5. doi: 10.1186/s40170-023-00305-3. Cancer Metab. 2023. PMID: 37085901 Free PMC article.
Short-term molecular consequences of chromosome mis-segregation for genome stability.
Garribba L, De Feudis G, Martis V, Galli M, Dumont M, Eliezer Y, Wardenaar R, Ippolito MR, Iyer DR, Tijhuis AE, Spierings DCJ, Schubert M, Taglietti S, Soriani C, Gemble S, Basto R, Rhind N, Foijer F, Ben-David U, Fachinetti D, Doksani Y, Santaguida S. Garribba L, et al. Nat Commun. 2023 Mar 11;14(1):1353. doi: 10.1038/s41467-023-37095-7. Nat Commun. 2023. PMID: 36906648 Free PMC article.
Inhalable Textile Microplastic Fibers Impair Airway Epithelial Differentiation.
Song S, van Dijk F, Vasse GF, Liu Q, Gosselink IF, Weltjens E, Remels AHV, de Jager MH, Bos S, Li C, Stoeger T, Rehberg M, Kutschke D, van Eck GWA, Wu X, Willems SH, Boom DHA, Kooter IM, Spierings D, Wardenaar R, Cole M, Nawijn MC, Salvati A, Gosens R, Melgert BN. Song S, et al. Am J Respir Crit Care Med. 2024 Feb 15;209(4):427-443. doi: 10.1164/rccm.202211-2099OC. Am J Respir Crit Care Med. 2024. PMID: 37971785
Late-Stage Metastatic Melanoma Emerges through a Diversity of Evolutionary Pathways.
Spain L, Coulton A, Lobon I, Rowan A, Schnidrig D, Shepherd STC, Shum B, Byrne F, Goicoechea M, Piperni E, Au L, Edmonds K, Carlyle E, Hunter N, Renn A, Messiou C, Hughes P, Nobbs J, Foijer F, van den Bos H, Wardenaar R, Spierings DCJ, Spencer C, Schmitt AM, Tippu Z, Lingard K, Grostate L, Peat K, Kelly K, Sarker S, Vaughan S, Mangwende M, Terry L, Kelly D, Biano J, Murra A, Korteweg J, Lewis C, O'Flaherty M, Cattin AL, Emmerich M, Gerard CL, Pallikonda HA, Lynch J, Mason R, Rogiers A, Xu H, Huebner A, McGranahan N, Al Bakir M, Murai J, Naceur-Lombardelli C, Borg E, Mitchison M, Moore DA, Falzon M, Proctor I, Stamp GWH, Nye EL, Young K, Furness AJS, Pickering L, Stewart R, Mahadeva U, Green A, Larkin J, Litchfield K, Swanton C, Jamal-Hanjani M; PEACE Consortium; Turajlic S. Spain L, et al. Cancer Discov. 2023 Jun 2;13(6):1364-1385. doi: 10.1158/2159-8290.CD-22-1427. Cancer Discov. 2023. PMID: 36977461 Free PMC article.
Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51.
Heijink AM, Stok C, Porubsky D, Manolika EM, de Kanter JK, Kok YP, Everts M, de Boer HR, Audrey A, Bakker FJ, Wierenga E, Tijsterman M, Guryev V, Spierings DCJ, Knipscheer P, van Boxtel R, Ray Chaudhuri A, Lansdorp PM, van Vugt MATM. Heijink AM, et al. Nat Commun. 2022 Nov 7;13(1):6722. doi: 10.1038/s41467-022-34519-8. Nat Commun. 2022. PMID: 36344511 Free PMC article.
91 results