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Targeting the m6A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication.
Burgess HM, Depledge DP, Thompson L, Srinivas KP, Grande RC, Vink EI, Abebe JS, Blackaby WP, Hendrick A, Albertella MR, Kouzarides T, Stapleford KA, Wilson AC, Mohr I. Burgess HM, et al. Among authors: srinivas kp. Genes Dev. 2021 Jul 1;35(13-14):1005-1019. doi: 10.1101/gad.348320.121. Epub 2021 Jun 24. Genes Dev. 2021. PMID: 34168039 Free PMC article.
Streptomyces sp metabolite(s) promotes Bax mediated intrinsic apoptosis and autophagy involving inhibition of mTOR pathway in cervical cancer cell lines.
Dan VM, Muralikrishnan B, Sanawar R, J S V, Burkul BB, Srinivas KP, Lekshmi A, Pradeep NS, Dastager SG, Santhakumari B, Santhoshkumar TR, Kumar RA, Pillai MR. Dan VM, et al. Among authors: srinivas kp. Sci Rep. 2018 Feb 12;8(1):2810. doi: 10.1038/s41598-018-21249-5. Sci Rep. 2018. PMID: 29434241 Free PMC article.