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Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development.
Lima A, Lubatti G, Burgstaller J, Hu D, Green AP, Di Gregorio A, Zawadzki T, Pernaute B, Mahammadov E, Perez-Montero S, Dore M, Sanchez JM, Bowling S, Sancho M, Kolbe T, Karimi MM, Carling D, Jones N, Srinivas S, Scialdone A, Rodriguez TA. Lima A, et al. Among authors: srinivas s. Nat Metab. 2021 Aug;3(8):1091-1108. doi: 10.1038/s42255-021-00422-7. Epub 2021 Jul 12. Nat Metab. 2021. PMID: 34253906 Free PMC article.
Defining murine organogenesis at single-cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation.
Ibarra-Soria X, Jawaid W, Pijuan-Sala B, Ladopoulos V, Scialdone A, Jörg DJ, Tyser RCV, Calero-Nieto FJ, Mulas C, Nichols J, Vallier L, Srinivas S, Simons BD, Göttgens B, Marioni JC. Ibarra-Soria X, et al. Among authors: srinivas s. Nat Cell Biol. 2018 Feb;20(2):127-134. doi: 10.1038/s41556-017-0013-z. Epub 2018 Jan 8. Nat Cell Biol. 2018. PMID: 29311656 Free PMC article.
A single-cell molecular map of mouse gastrulation and early organogenesis.
Pijuan-Sala B, Griffiths JA, Guibentif C, Hiscock TW, Jawaid W, Calero-Nieto FJ, Mulas C, Ibarra-Soria X, Tyser RCV, Ho DLL, Reik W, Srinivas S, Simons BD, Nichols J, Marioni JC, Göttgens B. Pijuan-Sala B, et al. Among authors: srinivas s. Nature. 2019 Feb;566(7745):490-495. doi: 10.1038/s41586-019-0933-9. Epub 2019 Feb 20. Nature. 2019. PMID: 30787436 Free PMC article.
Characterization of a common progenitor pool of the epicardium and myocardium.
Tyser RCV, Ibarra-Soria X, McDole K, Arcot Jayaram S, Godwin J, van den Brand TAH, Miranda AMA, Scialdone A, Keller PJ, Marioni JC, Srinivas S. Tyser RCV, et al. Among authors: srinivas s. Science. 2021 Mar 5;371(6533):eabb2986. doi: 10.1126/science.abb2986. Epub 2021 Jan 7. Science. 2021. PMID: 33414188 Free PMC article.
1,046 results