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The dimerization domain in DapE enzymes is required for catalysis.
Nocek B, Starus A, Makowska-Grzyska M, Gutierrez B, Sanchez S, Jedrzejczak R, Mack JC, Olsen KW, Joachimiak A, Holz RC. Nocek B, et al. Among authors: starus a. PLoS One. 2014 May 7;9(5):e93593. doi: 10.1371/journal.pone.0093593. eCollection 2014. PLoS One. 2014. PMID: 24806882 Free PMC article.
Indoline-6-Sulfonamide Inhibitors of the Bacterial Enzyme DapE.
Reidl CT, Heath TK, Darwish I, Torrez RM, Moore M, Gild E, Nocek BP, Starus A, Holz RC, Becker DP. Reidl CT, et al. Among authors: starus a. Antibiotics (Basel). 2020 Sep 11;9(9):595. doi: 10.3390/antibiotics9090595. Antibiotics (Basel). 2020. PMID: 32933028 Free PMC article.
Clearance of ctDNA in triple-negative and HER2-positive breast cancer patients during neoadjuvant treatment is correlated with pathologic complete response.
Ciriaco N, Zamora E, Escrivá-de-Romaní S, Miranda Gómez I, Jiménez Flores J, Saura C, Sloane H, Starus A, Fredebohm J, Georgieva L, Speight G, Jones F, Ramón Y Cajal S, Espinosa-Bravo M, Peg V. Ciriaco N, et al. Among authors: starus a. Ther Adv Med Oncol. 2022 Nov 29;14:17588359221139601. doi: 10.1177/17588359221139601. eCollection 2022. Ther Adv Med Oncol. 2022. PMID: 36479470 Free PMC article.