Staus DP - Search Results

1

Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.

Wingler LM, Skiba MA, McMahon C, Staus DP, Kleinhenz ALW, Suomivuori CM, Latorraca NR, Dror RO, Lefkowitz RJ, Kruse AC. Wingler LM, et al. Among authors: staus dp. Science. 2020 Feb 21;367(6480):888-892. doi: 10.1126/science.aay9813. Science. 2020. PMID: 32079768 Free PMC article.

2

Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling.

Paek J, Kalocsay M, Staus DP, Wingler L, Pascolutti R, Paulo JA, Gygi SP, Kruse AC. Paek J, et al. Among authors: staus dp. Cell. 2017 Apr 6;169(2):338-349.e11. doi: 10.1016/j.cell.2017.03.028. Cell. 2017. PMID: 28388415 Free PMC article.

3

G protein-coupled receptor kinases (GRKs) orchestrate biased agonism at the β₂-adrenergic receptor.

Choi M, Staus DP, Wingler LM, Ahn S, Pani B, Capel WD, Lefkowitz RJ. Choi M, et al. Among authors: staus dp. Sci Signal. 2018 Aug 21;11(544):eaar7084. doi: 10.1126/scisignal.aar7084. Sci Signal. 2018. PMID: 30131371

4

Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations.

Wingler LM, Elgeti M, Hilger D, Latorraca NR, Lerch MT, Staus DP, Dror RO, Kobilka BK, Hubbell WL, Lefkowitz RJ. Wingler LM, et al. Among authors: staus dp. Cell. 2019 Jan 24;176(3):468-478.e11. doi: 10.1016/j.cell.2018.12.005. Epub 2019 Jan 10. Cell. 2019. PMID: 30639099 Free PMC article.

5

Distinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic Nanobody.

Wingler LM, McMahon C, Staus DP, Lefkowitz RJ, Kruse AC. Wingler LM, et al. Among authors: staus dp. Cell. 2019 Jan 24;176(3):479-490.e12. doi: 10.1016/j.cell.2018.12.006. Epub 2019 Jan 10. Cell. 2019. PMID: 30639100 Free PMC article.

6

Structure of the M2 muscarinic receptor-β-arrestin complex in a lipid nanodisc.

Staus DP, Hu H, Robertson MJ, Kleinhenz ALW, Wingler LM, Capel WD, Latorraca NR, Lefkowitz RJ, Skiniotis G. Staus DP, et al. Nature. 2020 Mar;579(7798):297-302. doi: 10.1038/s41586-020-1954-0. Epub 2020 Jan 16. Nature. 2020. PMID: 31945772 Free PMC article.

7

Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor.

Suomivuori CM, Latorraca NR, Wingler LM, Eismann S, King MC, Kleinhenz ALW, Skiba MA, Staus DP, Kruse AC, Lefkowitz RJ, Dror RO. Suomivuori CM, et al. Among authors: staus dp. Science. 2020 Feb 21;367(6480):881-887. doi: 10.1126/science.aaz0326. Science. 2020. PMID: 32079767 Free PMC article.

8

Synthetic nanobodies as angiotensin receptor blockers.

McMahon C, Staus DP, Wingler LM, Wang J, Skiba MA, Elgeti M, Hubbell WL, Rockman HA, Kruse AC, Lefkowitz RJ. McMahon C, et al. Among authors: staus dp. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20284-20291. doi: 10.1073/pnas.2009029117. Epub 2020 Aug 4. Proc Natl Acad Sci U S A. 2020. PMID: 32753386 Free PMC article.

9

Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.

Shukla AK, Manglik A, Kruse AC, Xiao K, Reis RI, Tseng WC, Staus DP, Hilger D, Uysal S, Huang LY, Paduch M, Tripathi-Shukla P, Koide A, Koide S, Weis WI, Kossiakoff AA, Kobilka BK, Lefkowitz RJ. Shukla AK, et al. Among authors: staus dp. Nature. 2013 May 2;497(7447):137-41. doi: 10.1038/nature12120. Epub 2013 Apr 21. Nature. 2013. PMID: 23604254 Free PMC article.

10

Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies.

Staus DP, Wingler LM, Strachan RT, Rasmussen SG, Pardon E, Ahn S, Steyaert J, Kobilka BK, Lefkowitz RJ. Staus DP, et al. Mol Pharmacol. 2014 Mar;85(3):472-81. doi: 10.1124/mol.113.089516. Epub 2013 Dec 6. Mol Pharmacol. 2014. PMID: 24319111 Free PMC article.

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