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Drug design for G-protein-coupled receptors by a ligand-based NMR method.
Bartoschek S, Klabunde T, Defossa E, Dietrich V, Stengelin S, Griesinger C, Carlomagno T, Focken I, Wendt KU. Bartoschek S, et al. Among authors: stengelin s. Angew Chem Int Ed Engl. 2010 Feb 15;49(8):1426-9. doi: 10.1002/anie.200905102. Angew Chem Int Ed Engl. 2010. PMID: 20084646 No abstract available.
Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
Evers A, Bossart M, Pfeiffer-Marek S, Elvert R, Schreuder H, Kurz M, Stengelin S, Lorenz M, Herling A, Konkar A, Lukasczyk U, Pfenninger A, Lorenz K, Haack T, Kadereit D, Wagner M. Evers A, et al. Among authors: stengelin s. J Med Chem. 2018 Jul 12;61(13):5580-5593. doi: 10.1021/acs.jmedchem.8b00292. Epub 2018 Jun 25. J Med Chem. 2018. PMID: 29879354
Identification of the bile acid-binding site of the ileal lipid-binding protein by photoaffinity labeling, matrix-assisted laser desorption ionization-mass spectrometry, and NMR structure.
Kramer W, Sauber K, Baringhaus KH, Kurz M, Stengelin S, Lange G, Corsiero D, Girbig F, König W, Weyland C. Kramer W, et al. Among authors: stengelin s. J Biol Chem. 2001 Mar 9;276(10):7291-301. doi: 10.1074/jbc.M006877200. Epub 2000 Nov 7. J Biol Chem. 2001. PMID: 11069906 Free article.
Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part II).
Gao Z, Hurst WJ, Guillot E, Czechtizky W, Lukasczyk U, Nagorny R, Pruniaux MP, Schwink L, Sanchez JA, Stengelin S, Tang L, Winkler I, Hendrix JA, George PG. Gao Z, et al. Among authors: stengelin s. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3421-6. doi: 10.1016/j.bmcl.2013.03.081. Epub 2013 Mar 28. Bioorg Med Chem Lett. 2013. PMID: 23591112
Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part I).
Gao Z, Hurst WJ, Guillot E, Czechtizky W, Lukasczyk U, Nagorny R, Pruniaux MP, Schwink L, Sanchez JA, Stengelin S, Tang L, Winkler I, Hendrix JA, George PG. Gao Z, et al. Among authors: stengelin s. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3416-20. doi: 10.1016/j.bmcl.2013.03.080. Epub 2013 Mar 29. Bioorg Med Chem Lett. 2013. PMID: 23591110
32 results