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GDF15 neutralization restores muscle function and physical performance in a mouse model of cancer cachexia.
Cell Rep. 2023 Jan 31;42(1):111947. doi: 10.1016/j.celrep.2022.111947. Epub 2023 Jan 10.
Cell Rep. 2023.
PMID: 36640326
Free article.
GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates.
Breen DM, Kim H, Bennett D, Calle RA, Collins S, Esquejo RM, He T, Joaquim S, Joyce A, Lambert M, Lin L, Pettersen B, Qiao S, Rossulek M, Weber G, Wu Z, Zhang BB, Birnbaum MJ.
Breen DM, et al. Among authors: joaquim s.
Cell Metab. 2020 Dec 1;32(6):938-950.e6. doi: 10.1016/j.cmet.2020.10.023. Epub 2020 Nov 17.
Cell Metab. 2020.
PMID: 33207247
Free article.
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Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15.
Cimino I, Kim H, Tung YCL, Pedersen K, Rimmington D, Tadross JA, Kohnke SN, Neves-Costa A, Barros A, Joaquim S, Bennett D, Melvin A, Lockhart SM, Rostron AJ, Scott J, Liu H, Burling K, Barker P, Clatworthy MR, Lee EC, Simpson AJ, Yeo GSH, Moita LF, Bence KK, Jørgensen SB, Coll AP, Breen DM, O'Rahilly S.
Cimino I, et al. Among authors: joaquim s.
Proc Natl Acad Sci U S A. 2021 Jul 6;118(27):e2106868118. doi: 10.1073/pnas.2106868118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34187898
Free PMC article.
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Characterization of cachexia in the human fibrosarcoma HT-1080 mouse tumour model.
Bernardo B, Joaquim S, Garren J, Boucher M, Houle C, LaCarubba B, Qiao S, Wu Z, Esquejo RM, Peloquin M, Kim H, Breen DM.
Bernardo B, et al. Among authors: joaquim s.
J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1813-1829. doi: 10.1002/jcsm.12618. Epub 2020 Sep 13.
J Cachexia Sarcopenia Muscle. 2020.
PMID: 32924335
Free PMC article.
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Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation.
Breen DM, Jagarlapudi S, Patel A, Zou C, Joaquim S, Li X, Kang L, Pang J, Hales K, Ziso-Qejvanaj E, Vera NB, Bennett D, He T, Lambert M, Kelleher K, Wu Z, Zhang BB, Lin L, Seeley RJ, Bezy O.
Breen DM, et al. Among authors: joaquim s.
iScience. 2021 May 19;24(6):102554. doi: 10.1016/j.isci.2021.102554. eCollection 2021 Jun 25.
iScience. 2021.
PMID: 34189431
Free PMC article.
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