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Year | Number of Results |
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2023 | 5 |
2024 | 3 |
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Decrypting drug actions and protein modifications by dose- and time-resolved proteomics.
Science. 2023 Apr 7;380(6640):93-101. doi: 10.1126/science.ade3925. Epub 2023 Mar 16.
Science. 2023.
PMID: 36926954
Free PMC article.
Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors.
Reinecke M, Brear P, Vornholz L, Berger BT, Seefried F, Wilhelm S, Samaras P, Gyenis L, Litchfield DW, Médard G, Müller S, Ruland J, Hyvönen M, Wilhelm M, Kuster B.
Reinecke M, et al. Among authors: wilhelm s.
Nat Chem Biol. 2024 May;20(5):577-585. doi: 10.1038/s41589-023-01459-3. Epub 2023 Oct 30.
Nat Chem Biol. 2024.
PMID: 37904048
Free PMC article.
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An Introduction to Analytical Challenges, Approaches, and Applications in Mass Spectrometry-Based Secretomics.
Knecht S, Eberl HC, Kreisz N, Ugwu UJ, Starikova T, Kuster B, Wilhelm S.
Knecht S, et al. Among authors: wilhelm s.
Mol Cell Proteomics. 2023 Sep;22(9):100636. doi: 10.1016/j.mcpro.2023.100636. Epub 2023 Aug 18.
Mol Cell Proteomics. 2023.
PMID: 37597723
Free PMC article.
Review.
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Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition.
Kücükdisli M, Bel-Abed H, Cirillo D, Lo WT, Efrém NL, Horatscheck A, Perepelittchenko L, Prokofeva P, Ehret TAL, Radetzki S, Neuenschwander M, Specker E, Médard G, Müller S, Wilhelm S, Kuster B, von Kries JP, Haucke V, Nazaré M.
Kücükdisli M, et al. Among authors: wilhelm s.
J Med Chem. 2023 Oct 26;66(20):14278-14302. doi: 10.1021/acs.jmedchem.3c01319. Epub 2023 Oct 11.
J Med Chem. 2023.
PMID: 37819647
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Illuminating phenotypic drug responses of sarcoma cells to kinase inhibitors by phosphoproteomics.
Lee CY, The M, Meng C, Bayer FP, Putzker K, Müller J, Streubel J, Woortman J, Sakhteman A, Resch M, Schneider A, Wilhelm S, Kuster B.
Lee CY, et al. Among authors: wilhelm s.
Mol Syst Biol. 2024 Jan;20(1):28-55. doi: 10.1038/s44320-023-00004-7. Epub 2023 Dec 18.
Mol Syst Biol. 2024.
PMID: 38177929
Free PMC article.
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Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics.
Eckert S, Berner N, Kramer K, Schneider A, Müller J, Lechner S, Brajkovic S, Sakhteman A, Graetz C, Fackler J, Dudek M, Pfaffl MW, Knolle P, Wilhelm S, Kuster B.
Eckert S, et al. Among authors: wilhelm s.
Nat Biotechnol. 2024 May 7. doi: 10.1038/s41587-024-02218-y. Online ahead of print.
Nat Biotechnol. 2024.
PMID: 38714896
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