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The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus.
Sreedharan S, Almén MS, Carlini VP, Haitina T, Stephansson O, Sommer WH, Heilig M, de Barioglio SR, Fredriksson R, Schiöth HB. Sreedharan S, et al. Among authors: stephansson o. FEBS J. 2011 Dec;278(24):4881-94. doi: 10.1111/j.1742-4658.2011.08388.x. Epub 2011 Oct 31. FEBS J. 2011. PMID: 21981325 Free article.
mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts.
Caruso V, Sreedharan S, Carlini VP, Jacobsson JA, Haitina T, Hammer J, Stephansson O, Crona F, Sommer WH, Risérus U, Lannfelt L, Marcus C, Heilig M, de Barioglio SR, Fredriksson R, Schiöth HB. Caruso V, et al. Among authors: stephansson o. Gene. 2016 May 1;581(2):139-45. doi: 10.1016/j.gene.2016.01.044. Epub 2016 Jan 29. Gene. 2016. PMID: 26827797
267 results